Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.55 |
| ▸ | WNT3A | P56704 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | GNG2 | P59768 | 1/20 | 0.54 |
| ▸ | GNB1 | P62873 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.47 |
| ▸ | GSK3B | P49841 | 3/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22493225 | 1.00 | MAPT (0.56) | MAPTTDP1CTNNB1WNT3AALDH1A1 | |
| SCHEMBL15927509 | 1.00 | MAPT (0.56) | MAPTTDP1CTNNB1WNT3AALDH1A1 | |
| SCHEMBL1183589 | 0.98 | MAPT (0.57) | MAPTTDP1CTNNB1WNT3AALDH1A1 | |
| SCHEMBL1182899 | 0.95 | ALDH1A1 (0.61) | MAPTTDP1CTNNB1WNT3AALDH1A1 | |
| SCHEMBL15927500 | 0.91 | PTPN1 (0.52) | MAPTTDP1CTNNB1WNT3AALDH1A1 | |
| SCHEMBL15927490 | 0.84 | CTNNB1 (0.56) | MAPTTDP1CTNNB1WNT3AALDH1A1 | |
| SCHEMBL30089540 | 0.83 | CTNNB1 (0.73) | MAPTTDP1CTNNB1WNT3AALDH1A1 | |
| SCHEMBL22493258 | 0.82 | CTNNB1 (0.55) | MAPTTDP1CTNNB1WNT3AALDH1A1 | |
| SCHEMBL15927498 | 0.80 | CTNNB1 (0.56) | MAPTTDP1CTNNB1WNT3AALDH1A1 | |
| SCHEMBL15678862 | 0.80 | CTNNB1 (0.56) | MAPTTDP1CTNNB1WNT3AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3717475-B1 | KINASE INHIBITOR COMPOUNDS AND COMPOSITIONS AND METHODS OF USE | ICAHN SCHOOL MED MOUNT SINAI (US) | 2023-06-07 | — | — | EP | disclosed |
| WO-2014119617-A1 | AMIDINE COMPOUND AND SALT THEREOF | 富山化学工業株式会社 (JP) | 2014-08-07 | — | — | WO | disclosed |