Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15929082 | 1.00 | HTT (0.41) | HTTPKMALDH1A1KMT2ALMNA | |
| SCHEMBL14914787 | 0.88 | ALDH1A1 (0.41) | HTTPKMALDH1A1KMT2ALMNA | |
| SCHEMBL2594464 | 0.80 | GAA (0.47) | HTTPKMALDH1A1KMT2ALMNA | |
| SCHEMBL2477846 | 0.79 | HTT (0.47) | HTTPKMALDH1A1KMT2ALMNA | |
| SCHEMBL2473208 | 0.78 | GAA (0.43) | HTTPKMALDH1A1KMT2ALMNA | |
| SCHEMBL2473594 | 0.76 | HTT (0.44) | HTTPKMALDH1A1KMT2ALMNA | |
| SCHEMBL15929085 | 0.76 | MAPT (0.36) | HTTALDH1A1KMT2ALMNAMEN1 | |
| SCHEMBL3681334 | 0.76 | HTT (0.43) | HTTPKMALDH1A1KMT2ALMNA | |
| SCHEMBL3679553 | 0.76 | MAPT (0.43) | HTTPKMALDH1A1KMT2ALMNA | |
| SCHEMBL17669676 | 0.75 | HTT (0.50) | HTTPKMALDH1A1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8802860-B2 | Method for producing substituted pyridin-2-one | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-08-12 | — | — | US | disclosed |