SCHEMBL15929620

SCHEMBL15929620

COc1ccc(/C=C/C=C/C(=O)C(C)(C)C)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC8 Q9BY41 3/20 0.60
HDAC6 Q9UBN7 3/20 0.60
STAT3 P40763 1/20 0.60
F3 P13726 2/20 0.57
MAOB P27338 4/20 0.56
THRB P10828 1/20 0.56
ATM Q13315 1/20 0.56
KMT2A Q03164 3/20 0.55
ALDH1A1 P00352 2/20 0.55
MEN1 O00255 2/20 0.55
NPC1 O15118 1/20 0.55
LMNA P02545 1/20 0.55
RAB9A P51151 1/20 0.55
L3MBTL1 Q9Y468 1/20 0.55
MAOA P21397 1/20 0.55
CYP1A2 P05177 1/20 0.55
CYP2D6 P10635 1/20 0.55
GSK3B P49841 2/20 0.54
HDAC3 O15379 2/20 0.53
HDAC1 Q13547 2/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7771631 0.88 KMT2A (0.69) HDAC8HDAC6F3MAOBTHRB
SCHEMBL7771632 0.88 KMT2A (0.69) HDAC8HDAC6F3MAOBTHRB
SCHEMBL15929625 0.82 MAOB (0.55) MAOBKMT2AALDH1A1NPC1LMNA
SCHEMBL1231600 0.81 THRB (0.77) HDAC8HDAC6STAT3F3MAOB
SCHEMBL2026112 0.81 HDAC8 (0.65) HDAC8HDAC6STAT3F3MAOB
SCHEMBL1231605 0.81 THRB (0.77) HDAC8HDAC6STAT3F3MAOB
SCHEMBL2026113 0.81 HDAC8 (0.65) HDAC8HDAC6STAT3F3MAOB
SCHEMBL25307242 0.80 THRB (0.74) HDAC8HDAC6STAT3F3MAOB
SCHEMBL21428246 0.80 HDAC8 (0.68) HDAC8HDAC6STAT3F3MAOB
SCHEMBL16410058 0.80 HDAC8 (0.63) HDAC8HDAC6STAT3F3MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10551745-B2 Photopatternable compositions and methods of fabricating transistor devices using same FLEXTERRA, INC. (US) 2020-02-04 US disclosed
US-20170227846-A1 Photopatternable Compositions and Methods of Fabricating Transistor Devices Using Same USINVEST LLC 2017-08-10 US disclosed
US-20170227846-A1 Photopatternable Compositions and Methods of Fabricating Transistor Devices Using Same USINVEST LLC 2017-08-10 US disclosed
US-9704997-B2 Photopatternable materials and related electronic devices and methods FLEXTERRA, INC. (US) 2017-07-11 US disclosed
US-9704997-B2 Photopatternable materials and related electronic devices and methods FLEXTERRA, INC. (US) 2017-07-11 US disclosed
US-20170104080-A1 Curable Polymeric Materials and Their Use for Fabricating Electronic Devices USINVEST LLC 2017-04-13 US disclosed
US-20170104080-A1 Curable Polymeric Materials and Their Use for Fabricating Electronic Devices USINVEST LLC 2017-04-13 US disclosed
US-20160190337-A1 Photopatternable Materials and Related Electronic Devices and Methods USINVEST LLC 2016-06-30 US disclosed
US-9190493-B2 Photopatternable materials and related electronic devices and methods POLYERA CORPORATION (US) 2015-11-17 US disclosed
US-9035287-B2 Polymeric materials for use in metal-oxide-semiconductor field-effect transistors POLYERA CORPORATION (US) 2015-05-19 US disclosed
US-20150021597-A1 Photopatternable Materials and Related Electronic Devices and Methods USINVEST LLC 2015-01-22 US disclosed
US-20140217395-A1 Polymeric Materials for Use in Metal-Oxide-Semiconductor Field-Effect Transistors POLYERA CORPORATION (US) 2014-08-07 US disclosed