Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | ESR1 | P03372 | 4/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
| ▸ | ESRRG | P62508 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL635574 | 0.89 | ESR1 (0.52) | TSHRESR1ESR2CYP3A4AR | |
| SCHEMBL18901114 | 0.87 | TSHR (0.67) | TSHRESR1ESR2CYP3A4AR | |
| SCHEMBL4942966 | 0.87 | TSHR (0.67) | TSHRESR1ESR2CYP3A4AR | |
| SCHEMBL22737920 | 0.85 | TSHR (0.52) | TSHRACHETDP1ALDH1A1NPC1 | |
| SCHEMBL22738141 | 0.85 | TSHR (0.52) | TSHRESR1ESR2ACHETDP1 | |
| SCHEMBL16787954 | 0.82 | TSHR (0.48) | TSHRESR1ESR2CYP3A4AR | |
| SCHEMBL2742259 | 0.82 | TSHR (0.48) | TSHRESR1ESR2CYP3A4AR | |
| SCHEMBL72612 | 0.81 | — | — | |
| SCHEMBL16046945 | 0.80 | ESR1 (0.60) | TSHRESR1ESR2CYP3A4AR | |
| SCHEMBL24522303 | 0.79 | TSHR (0.83) | TSHRESR1ESR2CYP3A4AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021148556-A1 | PARTICLES OF (AZIRIDINYL HYDROXY)-FUNCTIONAL ORGANIC COMPOUNDS | COVESTRO (NETHERLANDS) B.V. (NL) | 2021-07-29 | — | — | WO | disclosed |
| US-9035287-B2 | Polymeric materials for use in metal-oxide-semiconductor field-effect transistors | POLYERA CORPORATION (US) | 2015-05-19 | — | — | US | disclosed |
| US-20140217395-A1 | Polymeric Materials for Use in Metal-Oxide-Semiconductor Field-Effect Transistors | POLYERA CORPORATION (US) | 2014-08-07 | — | — | US | disclosed |