SCHEMBL635574

SCHEMBL635574

CC(C)(c1ccc(S)cc1)c1ccc(S)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 4/20 0.52
TSHR P16473 4/20 0.52
ESR2 Q92731 3/20 0.52
HPGD P15428 3/20 0.52
CYP3A4 P08684 2/20 0.52
AR P10275 1/20 0.52
SLC6A2 P23975 1/20 0.52
SLC6A4 P31645 1/20 0.52
HTR6 P50406 1/20 0.52
ESRRG P62508 1/20 0.52
SLC6A3 Q01959 1/20 0.52
HSD17B10 Q99714 1/20 0.52
ALDH1A1 P00352 2/20 0.44
IDO1 P14902 1/20 0.38
PTPN11 Q06124 1/20 0.35
NR3C2 P08235 3/20 0.34
TP53 P04637 2/20 0.33
MAPT P10636 2/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16787954 0.92 TSHR (0.48) ESR1TSHRESR2HPGDCYP3A4
SCHEMBL2742259 0.92 TSHR (0.48) ESR1TSHRESR2HPGDCYP3A4
SCHEMBL15929632 0.89 TSHR (0.52) ESR1TSHRESR2HPGDCYP3A4
SCHEMBL16046945 0.89 ESR1 (0.60) ESR1TSHRESR2HPGDCYP3A4
SCHEMBL17563385 0.87 ESR1 (0.42) ESR1TSHRESR2HPGDCYP3A4
SCHEMBL15932978 0.87 ESR1 (0.76) ESR1TSHRESR2HPGDCYP3A4
SCHEMBL20350276 0.87 ESR1 (0.42) ESR1TSHRESR2HPGDCYP3A4
SCHEMBL19558108 0.87 IDO1 (0.62) ESR1TSHRESR2HPGDCYP3A4
SCHEMBL18651836 0.82 ALDH1A1 (0.46) ESR1TSHRESR2HPGDCYP3A4
SCHEMBL67741 0.81 TSHR (0.55) TSHRHPGDHSD17B10ALDH1A1IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 257 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260008903-A1 POLYTHIOL COMPOSITION AND USE THEREOF Efirm New Material Co., Ltd. (CN) 2026-01-08 US claimed
WO-2024188359-A1 POLYTHIOL COMPOSITION AND USE THEREOF 益丰新材料股份有限公司 2024-09-19 WO claimed
CN-117304082-A Polythiol compound for optical resin lens, optical resin lens and preparation method of optical resin lens 益丰新材料股份有限公司 2023-12-29 CN claimed
WO-2023147792-A1 POLYTHIOL COMPOSITION AND USE THEREOF 益丰新材料股份有限公司 2023-08-10 WO claimed
US-11377433-B2 Method for producing polyfunctional sulfur-containing epoxy compound MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2022-07-05 US claimed
US-20090163692-A1 AROMATIC POLYETHERS GENERAL ELECTRIC COMPANY (US) 2009-06-25 US claimed
US-6117923-A OXIDATION RESISTANCE. POLYMERIZING A NOVEL SULFUR-CONTAINING COMPOUND HAVING AN EPISULFIDE STRUCTURE MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2000-09-12 US claimed
US-4024162-A Aromatic dithio dianhydrides GENERAL ELECTRIC COMPANY (US) 1977-05-17 US claimed
US-12595338-B2 Process for preparing a hydroxy group functionalized thioether BASF SE (DE) 2026-04-07 US disclosed
EP-4714937-A1 METHOD FOR PRODUCING TETRAFUNCTIONAL THIOL WITH EPISULFIDE RESIN AS STARTING MATERIAL MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2026-03-25 EP disclosed
US-12552902-B2 Composition for optical material MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2026-02-17 US disclosed
US-20260008903-A1 POLYTHIOL COMPOSITION AND USE THEREOF Efirm New Material Co., Ltd. (CN) 2026-01-08 US disclosed
WO-2025089145-A1 POLYMERIZABLE COMPOSITION AND RESIN OBTAINED BY POLYMERIZING AND CURING SAME 三菱瓦斯化学株式会社 2025-05-01 WO disclosed
CN-119899615-A Repairable epoxy structural adhesive and preparation method thereof 广州集泰化工股份有限公司 2025-04-29 CN disclosed
US-5182340-A Molding materials having shorter gel time with aliphatic amine curing agents THE DOW CHEMICAL COMPANY (US) 1993-01-26 US disclosed
EP-0425049-A2 Polythiocarbonates and a process for their preparation ENICHEM S.p.A. (IT) 1991-05-02 EP disclosed
US-4024162-A Aromatic dithio dianhydrides GENERAL ELECTRIC COMPANY (US) 1977-05-17 US disclosed
US-3979369-A DIENE POLYMER MONSANTO COMPANY (US) 1976-09-07 US disclosed
US-3933749-A Polythioetherimides and method of preparation GENERAL ELECTRIC COMPANY (US) 1976-01-20 US disclosed
US-3933862-A Aromatic dithio dianhydrides GENERAL ELECTRIC COMPANY (US) 1976-01-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12552902-B2 Composition for optical material PAX2, RPL21, PAXBP1 ESR1 1171/4885TSHR 3601/4885ESR2 701/4885
US-12595338-B2 Process for preparing a hydroxy group functionalized thioether SCO2, SULT1E1, CYP2F1 ESR1 570/4885TSHR 791/4885ESR2 237/4885
US-20260008903-A1 POLYTHIOL COMPOSITION AND USE THEREOF PARG, C5, TAF1 ESR1 3965/4885TSHR 3763/4885ESR2 4049/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.