⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19763310 | 0.87 | HIF1A (0.36) | — | |
| SCHEMBL336591 | 0.87 | HIF1A (0.36) | — | |
| SCHEMBL19372394 | 0.86 | — | — | |
| SCHEMBL15928062 | 0.84 | HIF1A (0.39) | — | |
| SCHEMBL19102235 | 0.76 | — | — | |
| SCHEMBL16003052 | 0.76 | SOS1 (0.32) | — | |
| SCHEMBL490935 | 0.75 | — | — | |
| SCHEMBL18124124 | 0.74 | — | — | |
| SCHEMBL15929427 | 0.74 | — | — | |
| Piperazine SCHEMBL9824675 | 0.72 | HIF1A (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2788353-B1 | CAGE AMINE LIGANDS FOR METALLO-RADIOPHARMACEUTICALS | Clarity Pharmaceuticals Ltd (AU) | 2022-05-18 | — | — | EP | disclosed |
| US-20210030900-A1 | TARGETING COMPOUNDS AND METHODS FOR THEIR PRODUCTION | Clarity Pharmaceuticals Ltd (AU) | 2021-02-04 | — | — | US | disclosed |
| WO-2019195888-A1 | TARGETING COMPOUNDS AND METHODS FOR THEIR PRODUCTION | THE UNIVERSITY OF MELBOURNE (AU) | 2019-10-17 | — | — | WO | disclosed |
| US-20170290929-A1 | GRP78 TARGETED CONJUGATES | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2017-10-12 | — | — | US | disclosed |
| US-20140219915-A1 | CRYPTATE COMPOUNDS | AUSTRALIAN NUCLEAR SCIENCE AND TECHNOLOGY ORGANISATION (AU) | 2014-08-07 | — | — | US | disclosed |