SCHEMBL336591

SCHEMBL336591

NC12CNCCNCC(N)(CNCCNC1)CNCCNC2

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 1/20 0.36
MAPT P10636 1/20 0.36
PDE4A P27815 1/20 0.36
KDR P35968 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19763310 1.00 HIF1A (0.36) HIF1AMAPTPDE4AKDR
SCHEMBL15929702 0.87
SCHEMBL19102235 0.81
SCHEMBL19099007 0.81
SCHEMBL22236840 0.79
SCHEMBL18124124 0.79
SCHEMBL15929427 0.79
SCHEMBL25161936 0.75
SCHEMBL19372394 0.72
SCHEMBL490935 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 269 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122005879-A Modified GRPR antagonist peptides for cancer imaging and treatment 慕尼黑工业大学 2026-05-12 CN claimed
US-20260108637-A1 USES OF PSMA-TARGETING AND TSPO-TARGETING COMPOUNDS FOR EVALUATION OF INJURIES IN THE PERIPHERAL NERVOUS SYSTEM UNIV JOHNS HOPKINS (US) 2026-04-23 US claimed
EP-4719494-A2 USES OF PSMA-TARGETING AND TSPO-TARGETING COMPOUNDS FOR EVALUATION OF INJURIES IN THE PERIPHERAL NERVOUS SYSTEM The Johns Hopkins University (US) 2026-04-08 EP claimed
US-20250340701-A1 DENDRIMER-DELIVERED ALPHA-PARTICLE RADIOTHERAPY FOR TREATMENT OF GLIOBLASTOMA AND OTHER CANCERS IN THE BRAIN UNIV JOHNS HOPKINS (US) 2025-11-06 US claimed
US-12447217-B2 Fibroblast activation protein (FAP) inhibitors, FAP conjugates, and diagnostic and therapeutic uses thereof NUCLIDIUM AG (CH) 2025-10-21 US claimed
EP-4590345-A2 HIGH-PURITY COPPER RADIOPHARMACEUTICAL COMPOSITIONS AND DIAGNOSTIC AND THERAPEUTIC USES THEREOF Nuclidium AG (CH) 2025-07-30 EP claimed
EP-4590346-A1 FIBROBLAST ACTIVATION PROTEIN (FAP) INHIBITORS, FAP CONJUGATES, AND DIAGNOSTIC AND THERAPEUTIC USES THEREOF Nuclidium AG (CH) 2025-07-30 EP claimed
WO-2025151464-A1 ALPHA-PARTICLE RADIONUCLIDE-ANTIBODY CONJUGATES FOR TREATMENT OF SOLID TUMORS THE JOHNS HOPKINS UNIVERSITY (US) 2025-07-17 WO claimed
WO-2025125621-A1 CANCER-ASSOCIATED PROTEIN-TARGETED STRONG OR COVALENTLY BINDING PRECURSOR COMPOUNDS AND RADIOTRACERS RADIOVAXX GMBH (DE) 2025-06-19 WO claimed
CN-120022391-A Tumor PD-L1 targeted radioactive diagnosis and treatment drug, and labeling precursor, preparation method and application thereof 中国医学科学院药物研究所 2025-05-23 CN claimed
EP-3558395-A1 TUMOR AND IMMUNE CELL IMAGING BASED ON PD-L1 EXPRESSION The Johns Hopkins University (US) 2019-10-30 EP claimed
US-20190314531-A1 TUMOR AND IMMUNE CELL IMAGING BASED ON PD-L1 EXPRESSION THE JOHNS HOPKINS UNIVERSITY 2019-10-17 US claimed
WO-2018213537-A1 REAGENT FOR SITE-SELECTIVE BIOCONJUGATION OF PROTEINS OR ANTIBODIES RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK (US) 2018-11-22 WO claimed
WO-2018119313-A1 TUMOR AND IMMUNE CELL IMAGING BASED ON PD-L1 EXPRESSION THE JOHNS HOPKINS UNIVERSITY (US) 2018-06-28 WO claimed
US-9447149-B2 Methods and compositions for the rapid synthesis of radiometal-labeled probes UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2016-09-20 US claimed
US-20130108709-A1 TREATMENT OF MITOCHONDRIA-RELATED DISEASES AND IMPROVEMENT OF AGE-RELATED METABOLIC DEFICITS PROTEMIX CORPORATION LIMITED (NZ) 2013-05-02 US claimed
US-20100160428-A1 TREATMENT OF MITOCHONDRIA-RELATED DISEASES AND IMPROVEMENT OF AGE-RELATED METABOLIC DEFICITS PROTEMIX CORPORATION LIMITED (NZ) 2010-06-24 US claimed
EP-1948160-A1 TREATMENT OF MITOCHONDRIA-RELATED DISEASES AND IMPROVEMENT OF AGE-RELATED METABOLIC DEFICITS Protemix Corporation Limited (NZ) 2008-07-30 EP claimed
WO-2007055598-A1 TREATMENT OF MITOCHONDRIA-RELATED DISEASES AND IMPROVEMENT OF AGE-RELATED METABOLIC DEFICITS PROTEMIX CORPORATION LIMITED (NZ) 2007-05-18 WO claimed
WO-2006104396-A1 PRE-COMPLEXED COPPER ANTAGONIST COMPOSITIONS PROTEMIX CORPORATION LIMITED (NZ) 2006-10-05 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100160428-A1 TREATMENT OF MITOCHONDRIA-RELATED DISEASES AND IMPROVEMENT OF AGE-RELATED METABOLIC DEFICITS CS, GOT2, COX5B HIF1A 994/4885MAPT 529/4885PDE4A 297/4885
US-20130108709-A1 TREATMENT OF MITOCHONDRIA-RELATED DISEASES AND IMPROVEMENT OF AGE-RELATED METABOLIC DEFICITS TFAM, NDUFAB1, HSPA9 HIF1A 517/4885MAPT 468/4885PDE4A 911/4885
US-20250340701-A1 DENDRIMER-DELIVERED ALPHA-PARTICLE RADIOTHERAPY FOR TREATMENT OF GLIOBLASTOMA AND OTHER CANCERS IN THE BRAIN TUBA3E, TUBB2A, ADCYAP1R1 HIF1A 2042/4885MAPT 443/4885PDE4A 1093/4885
US-20260108637-A1 USES OF PSMA-TARGETING AND TSPO-TARGETING COMPOUNDS FOR EVALUATION OF INJURIES IN THE PERIPHERAL NERVOUS SYSTEM MUSK, TNNC1, TNNI3 HIF1A 3186/4885MAPT 2225/4885PDE4A 1707/4885
US-20190314531-A1 TUMOR AND IMMUNE CELL IMAGING BASED ON PD-L1 EXPRESSION CD274, PDCD1LG2, PDCD1 HIF1A 322/4885MAPT 749/4885PDE4A 4124/4885
US-12447217-B2 Fibroblast activation protein (FAP) inhibitors, FAP conjugates, and diagnostic and therapeutic uses thereof FAP, FIBP, FGFR1 HIF1A 2486/4885MAPT 2117/4885PDE4A 752/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.