Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.31 |
| ▸ | MAPT | P10636 | 4/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | CCR1 | P32246 | 2/20 | 0.31 |
| ▸ | CCR5 | P51681 | 2/20 | 0.31 |
| ▸ | CCR8 | P51685 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15930458 | 0.89 | HTR2A (0.34) | HTR2AHTR2CHTR2BKDM4EMAPT | |
| SCHEMBL15930344 | 0.86 | MAP4K1 (0.35) | HTR2AHTR2CHTR2BKDM4EMAPT | |
| SCHEMBL17809037 | 0.85 | MAP4K1 (0.35) | HTR2AHTR2CHTR2BKDM4EMAPT | |
| SCHEMBL15930334 | 0.85 | KDM4E (0.31) | KDM4EMAPTTDP1MEN1NPC1 | |
| SCHEMBL15930333 | 0.85 | L3MBTL1 (0.31) | KDM4EMAPTTDP1CCR1CCR5 | |
| SCHEMBL16275702 | 0.84 | MAP4K1 (0.31) | HTTAKT1MAP4K1AKT2AKT3 | |
| SCHEMBL16275795 | 0.84 | MAP4K1 (0.31) | HTTAKT1MAP4K1AKT2AKT3 | |
| SCHEMBL15930322 | 0.82 | AKT1 (0.30) | HTR2AHTR2CHTR2BKDM4EMAPT | |
| SCHEMBL15930323 | 0.82 | AKT1 (0.30) | HTR2AHTR2CHTR2BKDM4EMAPT | |
| SCHEMBL15930339 | 0.81 | MAP4K1 (0.31) | CCR1CCR5CCR8AKT1MAP4K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140217393-A1 | ORGANIC ELECTROLUMINESCENCE ELEMENT | IDEMITSU KOSAN CO., LTD. | 2014-08-07 | — | — | US | disclosed |
| US-20140217393-A1 | ORGANIC ELECTROLUMINESCENCE ELEMENT | IDEMITSU KOSAN CO., LTD. | 2014-08-07 | — | — | US | disclosed |