Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCQ | Q04759 | 16/20 | 0.49 |
| ▸ | PRKCD | Q05655 | 8/20 | 0.49 |
| ▸ | PRKCA | P17252 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9013504 | 0.83 | PRKCQ (0.72) | PRKCQPRKCDPRKCA | |
| SCHEMBL15930724 | 0.80 | PRKCQ (0.51) | PRKCQPRKCDPRKCAALDH1A1 | |
| SCHEMBL15930722 | 0.80 | PRKCQ (0.55) | PRKCQPRKCDPRKCAALDH1A1 | |
| SCHEMBL15930723 | 0.79 | PRKCQ (0.57) | PRKCQPRKCDPRKCAALDH1A1 | |
| SCHEMBL15930725 | 0.79 | PRKCQ (0.51) | PRKCQPRKCDPRKCAALDH1A1 | |
| SCHEMBL15930677 | 0.78 | PRKCQ (0.67) | PRKCQPRKCDPRKCAALDH1A1HDAC1 | |
| SCHEMBL15930676 | 0.78 | PRKCQ (0.67) | PRKCQPRKCDPRKCAALDH1A1 | |
| SCHEMBL15930669 | 0.78 | PRKCQ (0.67) | PRKCQPRKCDPRKCAALDH1A1HDAC1 | |
| SCHEMBL15930683 | 0.78 | PRKCQ (0.64) | PRKCQPRKCDPRKCAKMT2AALDH1A1 | |
| SCHEMBL15930675 | 0.76 | PRKCQ (0.67) | PRKCQPRKCDPRKCAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140221334-A1 | KINASE INHIBITORS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2014-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140221334-A1 | KINASE INHIBITORS | MAP3K20, MAP3K1, MAP3K6 | PRKCQ 38/4885PRKCD 120/4885PRKCA 25/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.