Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 1.00 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9371058 | 1.00 | HRH3 (1.00) | HRH3MAPTSIGMAR1CYP1A2MAPK1 | |
| SCHEMBL9126300 | 1.00 | HRH3 (1.00) | HRH3MAPTSIGMAR1CYP1A2MAPK1 | |
| SCHEMBL9370421 | 1.00 | HRH3 (1.00) | HRH3MAPTSIGMAR1CYP1A2MAPK1 | |
| SCHEMBL557955 | 1.00 | HRH3 (1.00) | HRH3MAPTSIGMAR1CYP1A2MAPK1 | |
| SCHEMBL3156252 | 1.00 | HRH3 (1.00) | HRH3MAPTSIGMAR1CYP1A2MAPK1 | |
| Bromide SCHEMBL10774236 | 0.97 | HRH3 (0.94) | HRH3MAPTSIGMAR1CYP1A2MAPK1 | |
| SCHEMBL15462284 | 0.97 | HRH3 (0.93) | HRH3MAPTSIGMAR1CYP1A2MAPK1 | |
| SCHEMBL1882477 | 0.97 | HRH3 (0.93) | HRH3MAPTSIGMAR1CYP1A2MAPK1 | |
| SCHEMBL15762056 | 0.97 | HRH3 (0.93) | HRH3MAPTSIGMAR1CYP1A2MAPK1 | |
| SCHEMBL5665906 | 0.97 | HRH3 (0.93) | HRH3MAPTSIGMAR1CYP1A2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2951188-B1 | PHOSPHORUS LIGANDS AND METHOD FOR THE SELECTIVE RUTHENIUM-CATALYZED HYDROAMINOMETHYLATION OF OLEFINS | EVONIK DEGUSSA GMBH (DE) | 2017-05-10 | — | — | EP | disclosed |
| EP-2951188-B1 | PHOSPHORUS LIGANDS AND METHOD FOR THE SELECTIVE RUTHENIUM-CATALYZED HYDROAMINOMETHYLATION OF OLEFINS | EVONIK DEGUSSA GMBH (DE) | 2017-05-10 | — | — | EP | disclosed |
| WO-2014118038-A1 | PHOSPHORUS LIGANDS AND METHOD FOR THE SELECTIVE RUTHENIUM-CATALYZED HYDROAMINOMETHYLATION OF OLEFINS | EVONIK INDUSTRIES AG (DE) | 2014-08-07 | — | — | WO | disclosed |