Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 1.00 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9371058 | 1.00 | HRH3 (1.00) | HRH3MAPTSIGMAR1CYP1A2MAPK1 | |
| SCHEMBL9126300 | 1.00 | HRH3 (1.00) | HRH3MAPTSIGMAR1CYP1A2MAPK1 | |
| SCHEMBL15933346 | 1.00 | HRH3 (1.00) | HRH3MAPTSIGMAR1CYP1A2MAPK1 | |
| SCHEMBL9370421 | 1.00 | HRH3 (1.00) | HRH3MAPTSIGMAR1CYP1A2MAPK1 | |
| SCHEMBL557955 | 1.00 | HRH3 (1.00) | HRH3MAPTSIGMAR1CYP1A2MAPK1 | |
| Bromide SCHEMBL10774236 | 0.97 | HRH3 (0.94) | HRH3MAPTSIGMAR1CYP1A2MAPK1 | |
| SCHEMBL15462284 | 0.97 | HRH3 (0.93) | HRH3MAPTSIGMAR1CYP1A2MAPK1 | |
| SCHEMBL1882477 | 0.97 | HRH3 (0.93) | HRH3MAPTSIGMAR1CYP1A2MAPK1 | |
| SCHEMBL15762056 | 0.97 | HRH3 (0.93) | HRH3MAPTSIGMAR1CYP1A2MAPK1 | |
| SCHEMBL5665906 | 0.97 | HRH3 (0.93) | HRH3MAPTSIGMAR1CYP1A2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-59148772-A | — | — | None | — | — | JP | disclosed |
| EP-3515898-B1 | PROCESS FOR THE PREPARATION OF POLYAMINES STARTING FROM DINITRILES AND/OR AMINONITRILES | BASF SE (DE) | 2020-11-11 | — | — | EP | disclosed |
| US-20190218341-A1 | METHOD FOR THE PREPARATION OF POLYAMINES FROM DINITRILES AND/OR AMINO NITRILES | BASF SE (DE) | 2019-07-18 | — | — | US | disclosed |
| WO-2018050555-A1 | METHOD FOR THE PREPARATION OF POLYAMINES FROM DINITRILES AND/OR AMINO NITRILES | BASF SE (DE) | 2018-03-22 | — | — | WO | disclosed |
| EP-1373208-B1 | A PROCESS FOR THE SYNTHESIS OF AN ALIPHATIC CYCLIC AMINE | COUNCIL SCIENT IND RES (IN) | 2010-03-10 | — | — | EP | disclosed |
| EP-1373208-A1 | A PROCESS FOR THE SYNTHESIS OF AN ALIPHATIC CYCLIC AMINE | Council of Scientific and Industrial Research (IN) | 2004-01-02 | — | — | EP | disclosed |
| US-6528647-B2 | Reacting dihydric alcohol characterized by four to six carbons, preferably 1,5-pentanediol, with excess ammonia in presence of ZSM-5 catalyst modified with nickel, copper or cobalt | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2003-03-04 | — | — | US | disclosed |
| US-20020183517-A1 | Process for the synthesis of an aliphatic cyclic amine | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH | 2002-12-05 | — | — | US | disclosed |
| WO-2002079160-A1 | A PROCESS FOR THE SYNTHESIS OF AN ALIPHATIC CYCLIC AMINE | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2002-10-10 | — | — | WO | disclosed |
| EP-0759914-B1 | TERTIARY DIAMINE, ITS USE AS CATALYST AND METHOD FOR PREPARATION OF TERTIARY DIAMINES | LONZA AG (CH) | 1998-09-23 | — | — | EP | disclosed |
| US-5698607-A | Tertiary diamine, its use as catalyst, and process for preparing tertiary diamines | LONZA AG (CH) | 1997-12-16 | — | — | US | disclosed |
| EP-0759914-A1 | TERTIARY DIAMINE, ITS USE AS CATALYST AND METHOD FOR PREPARATION OF TERTIARY DIAMINES | LONZA AG (CH) | 1997-03-05 | — | — | EP | disclosed |
| WO-1995030666-A1 | TERTIARY DIAMINE, ITS USE AS CATALYST AND METHOD FOR PREPARATION OF TERTIARY DIAMINES | LONZA AG (CH) | 1995-11-16 | — | — | WO | disclosed |
| JP-S59148772-A | PREPARATION OF HEXAMETHYLENEIMINE | MITSUBISHI PETROCHEM CO LTD | 1984-08-25 | — | — | JP | disclosed |
| US-4290946-A | CONTINUOUS PROCESSING, HEXAMETHYLENEDIAMINE | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1981-09-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190218341-A1 | METHOD FOR THE PREPARATION OF POLYAMINES FROM DINITRILES AND/OR AMINO NITRILES | SRM, PRMT1, HNMT | HRH3 371/4885MAPT 2101/4885SIGMAR1 1110/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.