Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 6/20 | 0.66 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.54 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.54 |
| ▸ | DRD3 | P35462 | 3/20 | 0.54 |
| ▸ | DRD2 | P14416 | 2/20 | 0.54 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.54 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.54 |
| ▸ | BCHE | P06276 | 2/20 | 0.53 |
| ▸ | ACHE | P22303 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8628519 | 1.00 | KCNH2 (0.66) | KCNH2HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL7167397 | 1.00 | KCNH2 (0.66) | KCNH2HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL11816138 | 1.00 | KCNH2 (0.66) | KCNH2HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL7231682 | 1.00 | KCNH2 (0.66) | KCNH2HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL8086700 | 1.00 | KCNH2 (0.66) | KCNH2HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL11097968 | 1.00 | KCNH2 (0.66) | KCNH2HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL11094954 | 1.00 | KCNH2 (0.66) | KCNH2HDAC3HDAC1HDAC2HDAC8 | |
| Hydrochloric Acid SCHEMBL11818106 | 0.98 | KCNH2 (0.64) | KCNH2HDAC3HDAC1HDAC2HDAC8 | |
| Hydrochloric Acid SCHEMBL5907917 | 0.98 | KCNH2 (0.64) | KCNH2HDAC3HDAC1HDAC2HDAC8 | |
| Bromide SCHEMBL28674611 | 0.98 | KCNH2 (0.64) | KCNH2HDAC3HDAC1HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2951188-B1 | PHOSPHORUS LIGANDS AND METHOD FOR THE SELECTIVE RUTHENIUM-CATALYZED HYDROAMINOMETHYLATION OF OLEFINS | EVONIK DEGUSSA GMBH (DE) | 2017-05-10 | — | — | EP | disclosed |
| EP-2951188-B1 | PHOSPHORUS LIGANDS AND METHOD FOR THE SELECTIVE RUTHENIUM-CATALYZED HYDROAMINOMETHYLATION OF OLEFINS | EVONIK DEGUSSA GMBH (DE) | 2017-05-10 | — | — | EP | disclosed |
| WO-2014118038-A1 | PHOSPHORUS LIGANDS AND METHOD FOR THE SELECTIVE RUTHENIUM-CATALYZED HYDROAMINOMETHYLATION OF OLEFINS | EVONIK INDUSTRIES AG (DE) | 2014-08-07 | — | — | WO | disclosed |