SCHEMBL15935573

SCHEMBL15935573

C[C@H]1CCCC[C@H]1Nc1nnc(C(N)=O)c(Nc2cc(-c3ccccc3)cc3c2ccn3C)n1

nearest known ligand 0.68

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ SYK P43405 20/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14839005 0.92 SYK (0.81) SYK
SCHEMBL14839074 0.81 SYK (1.00) SYK
SCHEMBL15910600 0.79 SYK (1.00) SYK
SCHEMBL16743276 0.77 SYK (0.80) SYK
SCHEMBL15910909 0.74 SYK (0.89) SYK
SCHEMBL14838933 0.74 SYK (1.00) SYK
SCHEMBL16743215 0.74 SYK (0.77) SYK
SCHEMBL15910572 0.72 SYK (0.80) SYK
SCHEMBL16253422 0.72 SYK (0.75) SYK
SCHEMBL14839159 0.72 SYK (0.75) SYK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2762476-A1 1,2,4-TRIAZINE-6-CARBOXAMIDE DERIVATIVE Taiho Pharmaceutical Co., Ltd. (JP) 2014-08-06 — — EP disclosed
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