Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 20/20 | 0.64 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16253403 | 0.89 | SYK (0.81) | SYKKCNH2 | |
| Hydrochloric Acid SCHEMBL15910632 | 0.88 | SYK (0.79) | SYKKCNH2 | |
| SCHEMBL15935586 | 0.83 | SYK (0.81) | SYK | |
| SCHEMBL16253439 | 0.80 | SYK (0.81) | SYKKCNH2 | |
| SCHEMBL14839079 | 0.78 | SYK (1.00) | SYKKCNH2 | |
| SCHEMBL14838963 | 0.77 | SYK (0.76) | SYKKCNH2 | |
| SCHEMBL15935568 | 0.76 | SYK (0.80) | SYKKCNH2 | |
| SCHEMBL16253443 | 0.74 | SYK (0.82) | SYK | |
| SCHEMBL14838892 | 0.74 | SYK (0.76) | SYKKCNH2 | |
| SCHEMBL14839054 | 0.72 | SYK (0.81) | SYKKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2762476-A1 | 1,2,4-TRIAZINE-6-CARBOXAMIDE DERIVATIVE | Taiho Pharmaceutical Co., Ltd. (JP) | 2014-08-06 | — | — | EP | disclosed |