SCHEMBL15935779

SCHEMBL15935779

Cc1cc(N=Nc2cc(C)c(N=Nc3c(S(=O)(=O)O)cc4cc(NC(=O)c5ccc(N)cc5)ccc4c3O)cc2C)c(C)cc1N=Nc1ccc(S(=O)(=O)O)cc1

nearest known ligand 0.64

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CD40 P25942 1/20 0.64
CD40LG P29965 1/20 0.64
ENPP2 Q13822 13/20 0.62
CASP6 P55212 1/20 0.55
CTDSP1 Q9GZU7 1/20 0.55
PRMT3 O60678 1/20 0.54
EP300 Q09472 1/20 0.54
PRMT6 Q96LA8 1/20 0.54
PRMT1 Q99873 1/20 0.54
CA2 P00918 1/20 0.49
CA3 P07451 1/20 0.49
ALDH1A1 P00352 1/20 0.47
HIF1A Q16665 1/20 0.47
MEN1 O00255 1/20 0.45
HTT P42858 1/20 0.45
KMT2A Q03164 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12830344 1.00 CD40 (0.64) CD40CD40LGENPP2CASP6CTDSP1
SCHEMBL19234925 1.00 CD40 (0.64) CD40CD40LGENPP2CASP6CTDSP1
SCHEMBL14388145 0.97 CD40 (0.61) CD40CD40LGENPP2CASP6CTDSP1
SCHEMBL14773570 0.97 CD40 (0.65) CD40CD40LGENPP2CASP6CTDSP1
SCHEMBL20735311 0.95 CD40 (0.61) CD40CD40LGENPP2CASP6CTDSP1
SCHEMBL19234922 0.95 CD40 (0.67) CD40CD40LGENPP2CASP6CTDSP1
SCHEMBL20747585 0.94 ENPP2 (0.68) CD40CD40LGENPP2CASP6CTDSP1
SCHEMBL19235084 0.94 ENPP2 (0.68) CD40CD40LGENPP2CASP6CTDSP1
SCHEMBL19234838 0.94 ENPP2 (0.68) CD40CD40LGENPP2CASP6CTDSP1
SCHEMBL13879484 0.94 ENPP2 (0.67) CD40CD40LGENPP2CASP6CTDSP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10209418-B2 Achromatic polarization element, and polarization plate NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2019-02-19 US disclosed
WO-2017135391-A1 POLARIZER ELEMENT, AND POLARIZING PLATE AND DISPLAY DEVICE USING SAME 日本化薬株式会社 2017-08-10 WO disclosed
US-20160041322-A1 Achromatic Polarization Element, And Polarization Plate NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2016-02-11 US disclosed
US-20140218797-A1 Polarizing Element And Polarizing Plate POLATECHNO CO., LTD. (JP) 2014-08-07 US disclosed