SCHEMBL15935816

COc1ccc(N=Nc2cc(C)c(N=Nc3cc(C)c(N=Nc4c(S(=O)(=O)O)cc5cc(NC(=O)c6ccccc6)ccc5c4O)cc3C)cc2C)c(S(=O)(=O)O)c1

nearest known ligand 0.60

Predicted protein targets (top 13)

	gene	UniProt	supporting neighbours	confidence
▸	ENPP2	Q13822	12/20	0.60

▸	CD40	P25942	1/20	0.53

▸	CD40LG	P29965	1/20	0.53

▸	PRMT1	Q99873	2/20	0.52

▸	PRMT3	O60678	1/20	0.52

▸	EP300	Q09472	1/20	0.52

▸	PRMT6	Q96LA8	1/20	0.52

▸	PHLPP2	Q6ZVD8	1/20	0.44

▸	CARM1	Q86X55	1/20	0.43

▸	NPC1	O15118	1/20	0.42

▸	RAB9A	P51151	1/20	0.42

▸	ALDH1A1	P00352	1/20	0.42

▸	HIF1A	Q16665	1/20	0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL19234799	1.00	ENPP2 (0.60)	ENPP2CD40CD40LGPRMT1PRMT3
SCHEMBL13879481	0.96	ENPP2 (0.59)	ENPP2CD40CD40LGPRMT1PRMT3
SCHEMBL19234803	0.92	ENPP2 (0.57)	ENPP2CD40CD40LGPRMT1PRMT3
SCHEMBL13879482	0.92	ENPP2 (0.57)	ENPP2CD40CD40LGPRMT1PRMT3
SCHEMBL11913411	0.89	ENPP2 (0.68)	ENPP2CD40CD40LGPRMT1PRMT3
SCHEMBL19234802	0.89	ENPP2 (0.65)	ENPP2CD40CD40LGPRMT1PRMT3
SCHEMBL14470019	0.89	ENPP2 (0.59)	ENPP2CD40CD40LGPRMT1PRMT3
SCHEMBL13880568	0.89	ENPP2 (0.59)	ENPP2CD40CD40LGPRMT1PRMT3
SCHEMBL12757652	0.86	ENPP2 (0.61)	ENPP2CD40CD40LGPRMT1PRMT3
SCHEMBL7906557	0.86	PRMT1 (0.66)	ENPP2CD40CD40LGPRMT1PRMT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20140218797-A1	Polarizing Element And Polarizing Plate	POLATECHNO CO., LTD. (JP)	2014-08-07	—	—	US	disclosed