SCHEMBL15935837

SCHEMBL15935837

Cc1cc(N=Nc2c(S(=O)(=O)O)cc3cc(NC(=O)c4ccc(N)cc4)ccc3c2O)c(C)cc1N=Nc1ccc(N=Nc2ccc(C(=O)O)cc2S(=O)(=O)O)c(C)c1

nearest known ligand 0.57

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ENPP2 Q13822 13/20 0.57
CD40 P25942 1/20 0.57
CD40LG P29965 1/20 0.57
PRMT3 O60678 1/20 0.49
EP300 Q09472 1/20 0.49
PRMT6 Q96LA8 1/20 0.49
PRMT1 Q99873 1/20 0.49
CASP6 P55212 1/20 0.46
CTDSP1 Q9GZU7 1/20 0.46
PHLPP2 Q6ZVD8 1/20 0.42
MEN1 O00255 1/20 0.42
HTT P42858 1/20 0.42
KMT2A Q03164 1/20 0.42
ALDH1A1 P00352 1/20 0.42
HIF1A Q16665 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13879478 0.93 ENPP2 (0.64) ENPP2CD40CD40LGPRMT3EP300
SCHEMBL19234804 0.92 ENPP2 (0.65) ENPP2CD40CD40LGPRMT3EP300
SCHEMBL19235017 0.92 ENPP2 (0.65) ENPP2CD40CD40LGPRMT3EP300
SCHEMBL15935793 0.92 ENPP2 (0.65) ENPP2CD40CD40LGPRMT3EP300
SCHEMBL13879484 0.91 ENPP2 (0.67) ENPP2CD40CD40LGPRMT3EP300
SCHEMBL14773570 0.91 CD40 (0.65) ENPP2CD40CD40LGPRMT3EP300
SCHEMBL14470019 0.90 ENPP2 (0.59) ENPP2CD40CD40LGPRMT3EP300
SCHEMBL19235076 0.89 ENPP2 (0.59) ENPP2CD40CD40LGPRMT3EP300
SCHEMBL19234798 0.89 ENPP2 (0.59) ENPP2CD40CD40LGPRMT3EP300
SCHEMBL19234922 0.89 CD40 (0.67) ENPP2CD40CD40LGPRMT3EP300

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017135391-A1 POLARIZER ELEMENT, AND POLARIZING PLATE AND DISPLAY DEVICE USING SAME 日本化薬株式会社 2017-08-10 WO disclosed
US-20140218797-A1 Polarizing Element And Polarizing Plate POLATECHNO CO., LTD. (JP) 2014-08-07 US disclosed