Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR3 | P22607 | 20/20 | 0.78 |
| ▸ | KDR | P35968 | 19/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20903348 | 0.89 | FGFR3 (0.87) | FGFR3KDR | |
| SCHEMBL15935881 | 0.88 | FGFR3 (1.00) | FGFR3KDR | |
| SCHEMBL11929524 | 0.86 | FGFR3 (1.00) | FGFR3KDR | |
| SCHEMBL11925857 | 0.83 | FGFR3 (1.00) | FGFR3KDR | |
| SCHEMBL3318312 | 0.81 | FGFR3 (0.84) | FGFR3KDR | |
| SCHEMBL3323299 | 0.81 | FGFR3 (1.00) | FGFR3KDR | |
| SCHEMBL11929124 | 0.80 | FGFR3 (1.00) | FGFR3KDR | |
| SCHEMBL11925929 | 0.80 | FGFR3 (1.00) | FGFR3KDR | |
| SCHEMBL11909608 | 0.80 | FGFR3 (1.00) | FGFR3KDR | |
| SCHEMBL3321669 | 0.79 | FGFR3 (0.82) | FGFR3KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8796244-B2 | Imidazopyridine derivatives as inhibitors of receptor tyrosine kinases | ASTEX THERAPEUTICS LTD (GB) | 2014-08-05 | — | — | US | disclosed |