Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR3 | P22607 | 20/20 | 0.87 |
| ▸ | KDR | P35968 | 19/20 | 0.87 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15935881 | 0.93 | FGFR3 (1.00) | FGFR3KDR | |
| SCHEMBL11929524 | 0.91 | FGFR3 (1.00) | FGFR3KDR | |
| SCHEMBL11925857 | 0.89 | FGFR3 (1.00) | FGFR3KDR | |
| SCHEMBL15935864 | 0.89 | FGFR3 (0.78) | FGFR3KDR | |
| SCHEMBL3323299 | 0.87 | FGFR3 (1.00) | FGFR3KDR | |
| SCHEMBL11909608 | 0.85 | FGFR3 (1.00) | FGFR3KDR | |
| SCHEMBL3318312 | 0.85 | FGFR3 (0.84) | FGFR3KDR | |
| SCHEMBL11929124 | 0.85 | FGFR3 (1.00) | FGFR3KDR | |
| SCHEMBL11925929 | 0.85 | FGFR3 (1.00) | FGFR3KDR | |
| SCHEMBL11909162 | 0.84 | FGFR3 (1.00) | FGFR3KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2300465-B1 | IMIDAZOPYRIDINE DERIVATIVES AS INHIBITORS OF RECEPTOR TYROSINE KINASES | ASTEX THERAPEUTICS LTD (GB) | 2019-04-17 | — | — | EP | disclosed |