Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 20/20 | 0.84 |
| ▸ | TXK | P42681 | 1/20 | 0.71 |
| ▸ | KARS1 | Q15046 | 1/20 | 0.71 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL373874 | 0.92 | SYK (1.00) | SYKTXKKARS1SLK | |
| SCHEMBL374082 | 0.89 | SYK (0.94) | SYKTXKKARS1SLK | |
| SCHEMBL15938660 | 0.87 | SYK (0.72) | SYKTXKKARS1SLK | |
| SCHEMBL374065 | 0.86 | SYK (1.00) | SYKTXKKARS1SLK | |
| SCHEMBL373973 | 0.86 | SYK (1.00) | SYKTXKKARS1SLK | |
| SCHEMBL13388960 | 0.84 | SYK (0.77) | SYKTXKKARS1SLK | |
| SCHEMBL373998 | 0.84 | SYK (0.94) | SYKTXKKARS1SLK | |
| SCHEMBL373922 | 0.83 | SYK (1.00) | SYKTXKKARS1SLK | |
| SCHEMBL373569 | 0.82 | SYK (1.00) | SYKTXKKARS1SLK | |
| SCHEMBL374177 | 0.81 | SYK (1.00) | SYKTXKKARS1SLK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140228374-A1 | Heterocyclic compounds, medicaments containing said compounds, use thereof and processes for the preparation thereof | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-08-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140228374-A1 | Heterocyclic compounds, medicaments containing said compounds, use thereof and processes for the preparation thereof | SCNN1B, SCNN1A, TRPM5 | SYK 1350/4885TXK 432/4885KARS1 2573/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.