Biphenyl

Biphenyl

SCHEMBL15940372

O=C(O)/C=C/c1ccccc1.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.86

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC2 Q92769 3/20 0.86
HCAR2 Q8TDS4 2/20 0.86
HDAC3 O15379 2/20 0.86
HDAC4 P56524 2/20 0.86
HDAC1 Q13547 2/20 0.86
HDAC8 Q9BY41 2/20 0.86
HDAC6 Q9UBN7 2/20 0.86
TNKS O95271 1/20 0.86
HDAC7 Q8WUI4 1/20 0.86
HDAC10 Q969S8 1/20 0.86
HDAC11 Q96DB2 1/20 0.86
TNKS2 Q9H2K2 1/20 0.86
HDAC9 Q9UKV0 1/20 0.86
HDAC5 Q9UQL6 1/20 0.86
PLIN1 O60240 2/20 0.64
LMNA P02545 2/20 0.64
MAPT P10636 2/20 0.64
RECQL P46063 2/20 0.64
PLIN5 Q00G26 2/20 0.64
ABHD5 Q8WTS1 2/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL15940373 1.00 HDAC2 (0.86) HDAC2HCAR2HDAC3HDAC4HDAC1
SCHEMBL165794 0.93 HDAC2 (0.75) HDAC2HCAR2HDAC3HDAC4HDAC1
SCHEMBL165795 0.93 HDAC2 (0.75) HDAC2HCAR2HDAC3HDAC4HDAC1
Cinnamic Acid SCHEMBL50466 0.93 HCAR2 (1.00) HDAC2HCAR2HDAC3HDAC4HDAC1
Cinnamic Acid SCHEMBL1706935 0.93 HCAR2 (1.00) HDAC2HCAR2HDAC3HDAC4HDAC1
Cinnamic Acid SCHEMBL1332 0.93 HCAR2 (1.00) HDAC2HCAR2HDAC3HDAC4HDAC1
Cinnamic Acid SCHEMBL653828 0.93 HCAR2 (1.00) HDAC2HCAR2HDAC3HDAC4HDAC1
Cinnamic Acid SCHEMBL3406486 0.93 HCAR2 (1.00) HDAC2HCAR2HDAC3HDAC4HDAC1
Cinnamic Acid SCHEMBL653827 0.93 HCAR2 (1.00) HDAC2HCAR2HDAC3HDAC4HDAC1
Cinnamic Acid SCHEMBL29989544 0.93 HCAR2 (1.00) HDAC2HCAR2HDAC3HDAC4HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8815000-B1 Solid inks comprising liquid crystalline materials XEROX CORPORATION (US) 2014-08-26 US claimed
US-20140225956-A1 SOLID INKS COMPRISING LIQUID CRYSTALLINE MATERIALS XEROX CORPORATION (US) 2014-08-14 US claimed
US-8815000-B1 Solid inks comprising liquid crystalline materials XEROX CORPORATION (US) 2014-08-26 US disclosed
US-20140225956-A1 SOLID INKS COMPRISING LIQUID CRYSTALLINE MATERIALS XEROX CORPORATION (US) 2014-08-14 US disclosed