Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 2/20 | 0.77 |
| ▸ | CA12 | O43570 | 1/20 | 0.61 |
| ▸ | CA1 | P00915 | 1/20 | 0.61 |
| ▸ | CA2 | P00918 | 1/20 | 0.61 |
| ▸ | CA9 | Q16790 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL266419 | 0.86 | MMP8 (0.74) | MMP8CA12CA1CA2CA9 | |
| SCHEMBL28474562 | 0.84 | MMP8 (0.73) | MMP8CA12CA1CA2CA9 | |
| SCHEMBL28674585 | 0.84 | MMP8 (0.72) | MMP8CA12CA1CA2CA9 | |
| SCHEMBL31069943 | 0.84 | MMP8 (0.72) | MMP8CA12CA1CA2CA9 | |
| Malonic Acid SCHEMBL25175314 | 0.83 | MMP8 (0.71) | MMP8CA12CA1CA2CA9 | |
| SCHEMBL1275691 | 0.82 | MMP8 (0.70) | MMP8CA12CA1CA2CA9 | |
| SCHEMBL2719749 | 0.81 | CA12 (0.70) | MMP8CA12CA1CA2CA9 | |
| SCHEMBL14783002 | 0.81 | CA12 (0.70) | MMP8CA12CA1CA2CA9 | |
| SCHEMBL6959479 | 0.81 | MMP8 (0.68) | MMP8CA12CA1CA2CA9 | |
| SCHEMBL583575 | 0.81 | MMP8 (0.68) | MMP8CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9056817-B2 | Arylated β-dicarbonyl compounds and process for the preparation thereof | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2015-06-16 | — | — | US | disclosed |
| US-20140228592-A1 | ARYLATED BETA-DICARBONYL COMPOUNDS AND PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2014-08-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140228592-A1 | ARYLATED BETA-DICARBONYL COMPOUNDS AND PROCESS FOR THE PREPARATION THEREOF | CYP51A1, DDT, CYP3A4 | MMP8 4860/4885CA12 301/4885CA1 631/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.