SCHEMBL15945680

SCHEMBL15945680

c1ccc(-n2c3ccc(-c4ccc(-c5ccc6c(c5)c5ccncc5n6-c5ccccc5)cc4)cc3c3ccncc32)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.46
ATM Q13315 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
DYRK1A Q13627 3/20 0.44
CDK4 P11802 3/20 0.42
CDK6 Q00534 3/20 0.42
KCNH2 Q12809 4/20 0.40
GSK3B P49841 1/20 0.40
CYP1A2 P05177 1/20 0.39
METAP2 P50579 1/20 0.39
MKNK1 Q9BUB5 1/20 0.37
AOC3 Q16853 3/20 0.37
NPY5R Q15761 1/20 0.37
MEN1 O00255 1/20 0.37
HSP90AA1 P07900 1/20 0.37
MAPT P10636 1/20 0.37
KMT2A Q03164 1/20 0.37
REN P00797 1/20 0.37
PIK3CA P42336 1/20 0.36
ALDH1A1 P00352 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25946458 0.98 KDM4E (0.44) KDM4EATML3MBTL1DYRK1ACDK4
SCHEMBL15945609 0.98 KDM4E (0.47) KDM4EATML3MBTL1DYRK1ACDK4
SCHEMBL15945677 0.97 KDM4E (0.51) KDM4EATML3MBTL1DYRK1ACDK4
SCHEMBL15945738 0.97 CDK4 (0.43) KDM4EATML3MBTL1DYRK1ACDK4
SCHEMBL15945688 0.97 CDK4 (0.43) KDM4EATML3MBTL1DYRK1ACDK4
SCHEMBL10309974 0.96 KDM4E (0.50) KDM4EATML3MBTL1DYRK1ACDK4
SCHEMBL15945585 0.95 KDM4E (0.53) KDM4EATML3MBTL1DYRK1ACDK4
SCHEMBL12114929 0.95 KDM4E (0.44) KDM4EATML3MBTL1DYRK1ACDK4
SCHEMBL15945736 0.95 CDK4 (0.42) KDM4EATML3MBTL1DYRK1ACDK4
SCHEMBL11965527 0.95 CDK4 (0.42) KDM4EATML3MBTL1DYRK1ACDK4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9627629-B2 Compound for organic optoelectronic device, organic light emitting diode including the same, and display including the organic light emitting diode SAMSUNG ELECTRONICS CO., LTD. (KR) 2017-04-18 US disclosed
US-9627629-B2 Compound for organic optoelectronic device, organic light emitting diode including the same, and display including the organic light emitting diode SAMSUNG ELECTRONICS CO., LTD. (KR) 2017-04-18 US disclosed
US-20140225088-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC LIGHT EMITTING DIODE INCLUDING THE SAME, AND DISPLAY INCLUDING THE ORGANIC LIGHT EMITTING DIODE CHEIL INDUSTRIES INC. (KR) 2014-08-14 US disclosed
US-20140225088-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC LIGHT EMITTING DIODE INCLUDING THE SAME, AND DISPLAY INCLUDING THE ORGANIC LIGHT EMITTING DIODE CHEIL INDUSTRIES INC. (KR) 2014-08-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140225088-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC LIGHT EMITTING DIODE INCLUDING THE SAME, AND DISPLAY INCLUDING THE ORGANIC LIGHT EMITTING DIODE OR10J3, AOX1, NR2E3 KDM4E 2599/4885ATM 1733/4885L3MBTL1 150/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.