SCHEMBL15945836

SCHEMBL15945836

CC1(C)c2cc(Oc3ccccc3)ccc2-c2cc3ccc4c5c(cc6ccc1c2c6c35)-c1ccc(Oc2ccccc2)cc1C4(C)C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 1/20 0.44
MAOB P27338 5/20 0.40
MAOA P21397 4/20 0.40
RXRA P19793 1/20 0.36
RXRB P28702 1/20 0.36
RXRG P48443 1/20 0.36
LTA4H P09960 3/20 0.35
GSTP1 P09211 1/20 0.34
TDP1 Q9NUW8 2/20 0.34
L3MBTL1 Q9Y468 2/20 0.34
TSHR P16473 1/20 0.33
MAPT P10636 1/20 0.33
PIM1 P11309 1/20 0.33
NPC1 O15118 1/20 0.33
MMP2 P08253 1/20 0.33
MMP3 P08254 1/20 0.33
MMP9 P14780 1/20 0.33
MMP8 P22894 1/20 0.33
MMP13 P45452 1/20 0.33
KDM1A O60341 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL431835 0.79 PDK2 (0.45) PDK2MAOBMAOALTA4HGSTP1
SCHEMBL12306515 0.79 MAOA (0.54) PDK2MAOBMAOATDP1MAPT
SCHEMBL14962020 0.78 PDK2 (0.40) PDK2MAOBMAOAGSTP1NPC1
SCHEMBL15197367 0.75 PDK2 (0.34) PDK2TDP1L3MBTL1MAPT
SCHEMBL12306559 0.75 MAOA (0.50) PDK2MAOBMAOAMAPT
SCHEMBL21974615 0.74 MAPK1 (0.46) PDK2MAOBMAOAGSTP1TDP1
SCHEMBL16153247 0.74 PDK2 (0.32) PDK2
SCHEMBL13206916 0.74 FFAR4 (0.45) PDK2MAOBMAOARXRARXRB
SCHEMBL12306556 0.73 MAOA (0.46) PDK2MAOBMAOAGSTP1NPC1
SCHEMBL12306553 0.72 MAOA (0.48) PDK2MAOBMAOAGSTP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11177450-B2 Organoelectroluminescent element, and light emission device, display device, and illumination device in which said organoelectroluminescent element is used UDC IRELAND LIMITED (IE) 2021-11-16 US disclosed
US-9608207-B2 Organic electroluminescence element UDC IRELAND LIMITED (IE) 2017-03-28 US disclosed
US-9608207-B2 Organic electroluminescence element UDC IRELAND LIMITED (IE) 2017-03-28 US disclosed
US-20140299851-A1 Organic Electroluminescence Element UDC IRELAND LIMITED (IE) 2014-10-09 US disclosed
US-20140299851-A1 Organic Electroluminescence Element UDC IRELAND LIMITED (IE) 2014-10-09 US disclosed
US-20140225085-A1 Organoelectroluminescent Element, and Light Emission Device, Display Device, and Illumination Device in which Said Organoelectroluminescent Element is Used UDC IRELAND LIMITED (IE) 2014-08-14 US disclosed
US-20140225085-A1 Organoelectroluminescent Element, and Light Emission Device, Display Device, and Illumination Device in which Said Organoelectroluminescent Element is Used UDC IRELAND LIMITED (IE) 2014-08-14 US disclosed