Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | RAC2 | P15153 | 1/20 | 0.33 |
| ▸ | RAC3 | P60763 | 1/20 | 0.33 |
| ▸ | CDC42 | P60953 | 1/20 | 0.33 |
| ▸ | RAC1 | P63000 | 1/20 | 0.33 |
| ▸ | TSPO | P30536 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | EDNRB | P24530 | 1/20 | 0.31 |
| ▸ | EDNRA | P25101 | 1/20 | 0.31 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.31 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.31 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.31 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18254309 | 1.00 | KDM4E (0.39) | KDM4EATML3MBTL1HDAC4RAC2 | |
| SCHEMBL14822239 | 0.98 | KDM4E (0.37) | KDM4EATML3MBTL1HDAC4RAC2 | |
| SCHEMBL14822608 | 0.97 | L3MBTL1 (0.39) | KDM4EATML3MBTL1HDAC4RAC2 | |
| SCHEMBL14822431 | 0.97 | L3MBTL1 (0.39) | KDM4EATML3MBTL1HDAC4RAC2 | |
| SCHEMBL782525 | 0.96 | L3MBTL1 (0.41) | KDM4EATML3MBTL1HDAC4RAC2 | |
| SCHEMBL14822255 | 0.96 | KDM4E (0.35) | KDM4EATML3MBTL1HDAC4RAC2 | |
| SCHEMBL16282965 | 0.96 | KDM4E (0.38) | KDM4EATML3MBTL1HDAC4RAC2 | |
| SCHEMBL15946302 | 0.95 | KDM4E (0.39) | KDM4EATML3MBTL1HDAC4RAC2 | |
| SCHEMBL14822532 | 0.95 | KDM4E (0.39) | KDM4EATML3MBTL1HDAC4RAC2 | |
| SCHEMBL15946296 | 0.95 | KDM4E (0.39) | KDM4EATML3MBTL1HDAC4RAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021037401-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2021-03-04 | — | — | WO | disclosed |
| US-9818948-B2 | Carbazole derivatives for organic electroluminescence devices | MERCK PATENT GMBH (DE) | 2017-11-14 | — | — | US | disclosed |
| US-9818948-B2 | Carbazole derivatives for organic electroluminescence devices | MERCK PATENT GMBH (DE) | 2017-11-14 | — | — | US | disclosed |
| EP-2758372-B1 | CARBAZOLE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2017-05-17 | — | — | EP | disclosed |
| US-20140364625-A1 | NOVEL ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME | ROHM & HAAS ELECT MAT (KR) | 2014-12-11 | — | — | US | disclosed |
| US-20140364625-A1 | NOVEL ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME | ROHM & HAAS ELECT MAT (KR) | 2014-12-11 | — | — | US | disclosed |
| US-20140225046-A1 | CARBAZOLE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENCE DEVICES | MERCK PATENT GMBH (DE) | 2014-08-14 | — | — | US | disclosed |
| US-20140225046-A1 | CARBAZOLE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENCE DEVICES | MERCK PATENT GMBH (DE) | 2014-08-14 | — | — | US | disclosed |