Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 4/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
| ▸ | TSPO | P30536 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.31 |
| ▸ | IL1R1 | P14778 | 1/20 | 0.31 |
| ▸ | RXRA | P19793 | 1/20 | 0.30 |
| ▸ | RXRB | P28702 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | HTT | P42858 | 2/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HBB | P68871 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29694589 | 1.00 | L3MBTL1 (0.44) | L3MBTL1KDM4EATMPGRPTGER4 | |
| SCHEMBL10001493 | 1.00 | L3MBTL1 (0.44) | L3MBTL1KDM4EATMPGRPTGER4 | |
| SCHEMBL15337978 | 0.99 | KDM4E (0.43) | L3MBTL1KDM4EATMPGRPTGER4 | |
| SCHEMBL14822513 | 0.98 | KDM4E (0.42) | L3MBTL1KDM4EATMPGRPTGER4 | |
| SCHEMBL14822420 | 0.98 | KDM4E (0.42) | L3MBTL1KDM4EATMPGRPTGER4 | |
| SCHEMBL20129503 | 0.98 | KDM4E (0.42) | L3MBTL1KDM4EATMPGRPTGER4 | |
| SCHEMBL16641313 | 0.98 | KDM4E (0.42) | L3MBTL1KDM4EATMPGRPTGER4 | |
| SCHEMBL14849836 | 0.98 | KDM4E (0.42) | L3MBTL1KDM4EATMPGRPTGER4 | |
| SCHEMBL16282967 | 0.98 | KDM4E (0.42) | L3MBTL1KDM4EATMPGRPTGER4 | |
| SCHEMBL16283013 | 0.96 | L3MBTL1 (0.41) | L3MBTL1KDM4EATMPGRPTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9818948-B2 | Carbazole derivatives for organic electroluminescence devices | MERCK PATENT GMBH (DE) | 2017-11-14 | — | — | US | disclosed |
| US-9818948-B2 | Carbazole derivatives for organic electroluminescence devices | MERCK PATENT GMBH (DE) | 2017-11-14 | — | — | US | disclosed |
| US-20140225046-A1 | CARBAZOLE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENCE DEVICES | MERCK PATENT GMBH (DE) | 2014-08-14 | — | — | US | disclosed |
| US-20140225046-A1 | CARBAZOLE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENCE DEVICES | MERCK PATENT GMBH (DE) | 2014-08-14 | — | — | US | disclosed |