Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A1 | P43005 | 4/20 | 0.57 |
| ▸ | SLC1A3 | P43003 | 4/20 | 0.57 |
| ▸ | SLC1A2 | P43004 | 4/20 | 0.57 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.43 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.43 |
| ▸ | FYN | P06241 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13623320 | 0.89 | SLC1A1 (0.57) | SLC1A1SLC1A3SLC1A2GRM2GRM3 | |
| SCHEMBL2777585 | 0.87 | SLC7A5 (0.57) | KDM4EUSP2EGFRLCKFYN | |
| SCHEMBL2777583 | 0.87 | SLC7A5 (0.57) | KDM4EUSP2EGFRLCKFYN | |
| SCHEMBL31734664 | 0.87 | SLC7A5 (0.57) | KDM4EUSP2EGFRLCKFYN | |
| SCHEMBL6774498 | 0.87 | SLC7A5 (0.57) | KDM4EUSP2EGFRLCKFYN | |
| Hydrochloric Acid SCHEMBL6770667 | 0.85 | SLC7A5 (0.55) | KDM4EUSP2EGFRLCKFYN | |
| Hydrochloric Acid SCHEMBL6770660 | 0.85 | SLC7A5 (0.55) | KDM4EUSP2EGFRLCKFYN | |
| Hydrochloric Acid SCHEMBL5367785 | 0.85 | SLC7A5 (0.55) | KDM4EUSP2EGFRLCKFYN | |
| SCHEMBL13464177 | 0.84 | SLC1A1 (0.59) | SLC1A1SLC1A3SLC1A2GRM2GRM3 | |
| SCHEMBL12656312 | 0.82 | SLC1A1 (0.59) | SLC1A1SLC1A3SLC1A2GRM2GRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140227191-A1 | L-GLUTAMIC ACID AND L-GLUTAMINE DERIVATIVE (III), USE THEREOF AND METHOD FOR OBTAINING THEM | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2014-08-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140227191-A1 | L-GLUTAMIC ACID AND L-GLUTAMINE DERIVATIVE (III), USE THEREOF AND METHOD FOR OBTAINING THEM | GLUL, GATD3, QPCT | SLC1A1 6/4885SLC1A3 5/4885SLC1A2 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.