Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 5/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.56 |
| ▸ | F3 | P13726 | 1/20 | 0.56 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.52 |
| ▸ | ALB | P02768 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | GLI1 | P08151 | 1/20 | 0.52 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.52 |
| ▸ | NT5E | P21589 | 1/20 | 0.52 |
| ▸ | DPP4 | P27487 | 1/20 | 0.52 |
| ▸ | RORC | P51449 | 1/20 | 0.52 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.52 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15917888 | 0.91 | GPBAR1 (0.62) | GPBAR1PTPN1F3USP2LMNA | |
| SCHEMBL15918172 | 0.91 | GPBAR1 (0.70) | GPBAR1PTPN1USP2LMNAHIF1A | |
| SCHEMBL18513850 | 0.91 | RORC (0.58) | GPBAR1PTPN1F3PRKCDUSP2 | |
| SCHEMBL23284128 | 0.89 | GPBAR1 (0.69) | GPBAR1PRKCD | |
| SCHEMBL22251684 | 0.89 | GPBAR1 (0.69) | GPBAR1PRKCD | |
| SCHEMBL16512011 | 0.89 | GPBAR1 (0.69) | GPBAR1PRKCD | |
| SCHEMBL9108438 | 0.89 | GPBAR1 (0.69) | GPBAR1PRKCD | |
| SCHEMBL12593102 | 0.89 | PTPN1 (0.70) | GPBAR1PTPN1F3USP2LMNA | |
| SCHEMBL12558298 | 0.89 | PTPN1 (0.70) | GPBAR1PTPN1F3USP2LMNA | |
| SCHEMBL5534963 | 0.89 | PTPN1 (0.70) | GPBAR1PTPN1F3USP2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014123889-A1 | C-19 MODIFIED TRITERPENOIDS WITH HIV MATURATION INHIBITORY ACTIVITY | BRISTOL-MYERS SQUIBB COMPANY (US) | 2014-08-14 | — | — | WO | disclosed |