Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 2/20 | 0.47 |
| ▸ | RXRB | P28702 | 1/20 | 0.47 |
| ▸ | RXRG | P48443 | 1/20 | 0.47 |
| ▸ | PTGER1 | P34995 | 4/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 4/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.42 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.42 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.42 |
| ▸ | ERN1 | O75460 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15942231 | 1.00 | RXRA (0.47) | RXRARXRBRXRGPTGER1MCL1 | |
| SCHEMBL15942232 | 1.00 | RXRA (0.47) | RXRARXRBRXRGPTGER1MCL1 | |
| SCHEMBL21022931 | 0.92 | PTGER1 (0.42) | RXRARXRBRXRGPTGER1MCL1 | |
| SCHEMBL17402231 | 0.91 | RXRA (0.47) | RXRARXRBRXRGPTGER1MCL1 | |
| SCHEMBL15941028 | 0.91 | RXRA (0.49) | RXRARXRBRXRGPTGER1MCL1 | |
| SCHEMBL15942310 | 0.91 | RXRA (0.49) | RXRARXRBRXRGPTGER1MCL1 | |
| SCHEMBL15941208 | 0.91 | RXRA (0.49) | RXRARXRBRXRGPTGER1MCL1 | |
| SCHEMBL15942243 | 0.91 | RXRA (0.49) | RXRARXRBRXRGPTGER1MCL1 | |
| SCHEMBL17389334 | 0.91 | RXRA (0.49) | RXRARXRBRXRGPTGER1MCL1 | |
| SCHEMBL17389349 | 0.87 | RXRA (0.44) | RXRARXRBRXRGPTGER1MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014122664-A1 | LANTHANIDE CLUSTERS AND METHODS OF USE THEREOF | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2014-08-14 | — | — | WO | disclosed |