Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 7/20 | 0.56 |
| ▸ | FAAH | O00519 | 1/20 | 0.52 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | IGF1R | P08069 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1595469 | 0.92 | EPHX2 (0.51) | EPHX2FAAHMCHR1NPC1RAB9A | |
| SCHEMBL2571500 | 0.89 | EPHX2 (0.50) | EPHX2FAAHMCHR1NPC1RAB9A | |
| SCHEMBL2570527 | 0.88 | EPHX2 (0.49) | EPHX2FAAHMCHR1NPC1RAB9A | |
| SCHEMBL1594485 | 0.87 | EPHX2 (0.59) | EPHX2FAAHMCHR1NPC1RAB9A | |
| SCHEMBL2567978 | 0.87 | EPHX2 (0.53) | EPHX2FAAHNPC1RAB9AIGF1R | |
| SCHEMBL1594683 | 0.86 | EPHX2 (0.50) | EPHX2FAAHNPC1RAB9APOLB | |
| SCHEMBL2571142 | 0.86 | EPHX2 (0.54) | EPHX2FAAHMCHR1NPC1RAB9A | |
| SCHEMBL2876477 | 0.86 | EPHX2 (0.49) | EPHX2FAAHMCHR1NPC1RAB9A | |
| SCHEMBL2881513 | 0.85 | EPHX2 (0.49) | EPHX2FAAHNPC1RAB9AIGF1R | |
| SCHEMBL1595202 | 0.85 | EPHX2 (0.51) | EPHX2FAAHNPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103889973-B | The sulfonate of the imidazoles of heterocyclyl amides substitution | 爱库利斯有限两合公司 | 2017-12-05 | — | — | CN | disclosed |
| EP-2755964-B1 | SULFONIC ACID SALTS OF HETEROCYCLYLAMIDE-SUBSTITUTED IMIDAZOLES | AICURIS ANTI INFECTIVE CURES GMBH (DE) | 2016-06-22 | — | — | EP | disclosed |
| EP-2755964-B1 | SULFONIC ACID SALTS OF HETEROCYCLYLAMIDE-SUBSTITUTED IMIDAZOLES | AICURIS ANTI INFECTIVE CURES GMBH (DE) | 2016-06-22 | — | — | EP | disclosed |
| US-9133165-B2 | Sulfonic acid salts of heterocyclylamide-substituted imidazoles | AICURIS GMBH & CO. KG (DE) | 2015-09-15 | — | — | US | disclosed |
| US-9133165-B2 | Sulfonic acid salts of heterocyclylamide-substituted imidazoles | AICURIS GMBH & CO. KG (DE) | 2015-09-15 | — | — | US | disclosed |
| US-20140315924-A1 | SULFONIC ACID SALTS OF HETEROCYCLYLAMIDE-SUBSTITUTED IMIDAZOLES | AICURIS GMBH & CO. KG (DE) | 2014-10-23 | — | — | US | disclosed |
| US-20140315924-A1 | SULFONIC ACID SALTS OF HETEROCYCLYLAMIDE-SUBSTITUTED IMIDAZOLES | AICURIS GMBH & CO. KG (DE) | 2014-10-23 | — | — | US | disclosed |
| EP-2755964-A1 | SULFONIC ACID SALTS OF HETEROCYCLYLAMIDE-SUBSTITUTED IMIDAZOLES | AiCuris GmbH & Co. KG (DE) | 2014-07-23 | — | — | EP | disclosed |
| CN-103889973-A | SULFONIC ACID SALTS OF HETEROCYCLYLAMIDE-SUBSTITUTED IMIDAZOLES | AICURIS GMBH & CO KG | 2014-06-25 | — | — | CN | disclosed |
| WO-2013037812-A1 | SULFONIC ACID SALTS OF HETEROCYCLYLAMIDE-SUBSTITUTED IMIDAZOLES | AICURIS GMBH & CO. KG (DE) | 2013-03-21 | — | — | WO | disclosed |
| EP-1853582-B1 | HETEROCYCLYLAMIDE-SUBSTITUTED IMIDAZOLES | AICURIS GMBH & CO KG (DE) | 2009-10-21 | — | — | EP | disclosed |
| US-20080176859-A1 | HETEROCYCLYAMIDE-SUBSTITUTED IMIDAZOLES | AICURIS GMBH & CO. KG (DE) | 2008-07-24 | — | — | US | disclosed |
| US-20080176859-A1 | HETEROCYCLYAMIDE-SUBSTITUTED IMIDAZOLES | AICURIS GMBH & CO. KG (DE) | 2008-07-24 | — | — | US | disclosed |
| US-20080176859-A1 | HETEROCYCLYAMIDE-SUBSTITUTED IMIDAZOLES | AICURIS GMBH & CO. KG (DE) | 2008-07-24 | — | — | US | disclosed |
| CN-101128455-A | Heterocyclylamide-substituted imidazoles | BAYER HEALTHCARE AG (DE) | 2008-02-20 | — | — | CN | disclosed |
| US-20080004275-A1 | Antiviral 4-Aminocarbonylamino-Substituted Imidazole Compounds | BAYER HEALTHCARE AG (DE) | 2008-01-03 | — | — | US | disclosed |
| US-20080004275-A1 | Antiviral 4-Aminocarbonylamino-Substituted Imidazole Compounds | BAYER HEALTHCARE AG (DE) | 2008-01-03 | — | — | US | disclosed |
| US-20080004275-A1 | Antiviral 4-Aminocarbonylamino-Substituted Imidazole Compounds | BAYER HEALTHCARE AG (DE) | 2008-01-03 | — | — | US | disclosed |
| EP-1853582-A2 | HETEROCYCLYLAMIDE-SUBSTITUTED IMIDAZOLES | AiCuris GmbH & Co. KG (DE) | 2007-11-14 | — | — | EP | disclosed |
| WO-2006089664-A2 | HETEROCYCLYLAMIDE-SUBSTITUTED IMIDAZOLES | AICURIS GMBH & CO. KG (DE) | 2006-08-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080176859-A1 | HETEROCYCLYAMIDE-SUBSTITUTED IMIDAZOLES | TPMT, TYMP, PAICS | EPHX2 2438/4885FAAH 2072/4885MCHR1 4539/4885 |
| US-20140315924-A1 | SULFONIC ACID SALTS OF HETEROCYCLYLAMIDE-SUBSTITUTED IMIDAZOLES | TPMT, MPST, STS | EPHX2 2129/4885FAAH 1715/4885MCHR1 4218/4885 |
| US-20080004275-A1 | Antiviral 4-Aminocarbonylamino-Substituted Imidazole Compounds | IRF3, EIF2AK2, ZC3HAV1 | EPHX2 3922/4885FAAH 3850/4885MCHR1 4719/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.