Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL1594791

C=CCC(c1ccccc1)S(=O)(=O)O.N

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 2/20 0.56
SRC P12931 2/20 0.47
ALDH1A1 P00352 3/20 0.42
SMN1; SMN2 Q16637 2/20 0.40
KDM4E B2RXH2 2/20 0.36
MAPT P10636 2/20 0.36
CYP2D6 P10635 1/20 0.36
ALOX15 P16050 1/20 0.36
HSD17B10 Q99714 1/20 0.36
KMT2A Q03164 2/20 0.35
LMNA P02545 3/20 0.35
MAPK1 P28482 1/20 0.35
OPRD1 P41143 1/20 0.35
HSD11B1 P28845 1/20 0.34
GMNN O75496 1/20 0.34
POLB P06746 1/20 0.34
HPGD P15428 1/20 0.34
PMP22 Q01453 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
TDP1 Q9NUW8 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL982815 0.98 CYP2C19 (0.58) CYP2C19SRCALDH1A1SMN1; SMN2KDM4E
SCHEMBL27504829 0.96 CYP2C19 (0.56) CYP2C19SRCALDH1A1SMN1; SMN2KDM4E
Succinic Acid SCHEMBL27674622 0.90 CYP2C19 (0.54) CYP2C19SRCALDH1A1SMN1; SMN2CYP2D6
SCHEMBL10944451 0.81 SRC (0.50) CYP2C19SRCALDH1A1SMN1; SMN2KDM4E
SCHEMBL11825005 0.81 GABBR2 (0.42) CYP2C19CYP2D6HSD17B10KMT2ALMNA
SCHEMBL2991652 0.81 CYP2C19 (0.46) CYP2C19SRCALDH1A1KDM4EMAPT
SCHEMBL7580947 0.80 CYP2C19 (0.49) CYP2C19ALDH1A1SMN1; SMN2KDM4EMAPT
SCHEMBL28154652 0.80 SRC (0.48) CYP2C19SRCALDH1A1SMN1; SMN2KDM4E
SCHEMBL10469067 0.79 CYP2C19 (0.45) CYP2C19SRCALDH1A1SMN1; SMN2KDM4E
SCHEMBL13970191 0.79 CYP2C19 (0.47) CYP2C19SRCALDH1A1SMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2047270-A2 STABILIZING AGENTS AND CAPTURE LIGANDS FOR USE IN ASSAYS MEASURING ANALYTE CONCENTRATIONS BECKMAN Coulter, Inc. (US) 2009-04-15 EP claimed
US-20080182341-A1 Stabilizing agents and capture ligands for use in assays measuring analyte concentrations BECKMAN COULTER, INC. 2008-07-31 US claimed
WO-2008039266-A2 STABILIZING AGENTS AND CAPTURE LIGANDS FOR USE IN ASSAYS MEASURING ANALYTE CONCENTRATIONS BECKMAN COULTER, INC. (US) 2008-04-03 WO claimed
EP-2047270-B1 STABILIZING AGENTS AND CAPTURE LIGANDS FOR USE IN ASSAYS MEASURING ANALYTE CONCENTRATIONS BECKMAN COULTER INC (US) 2013-09-04 EP disclosed
US-8450073-B2 Stabilizing agents and capture ligands for use in assays measuring analyte concentrations BECKMAN COULTER, INC. (US) 2013-05-28 US disclosed
US-20110091909-A1 Stabilizing Agents and Capture Ligands for Use in Assays Measuring Analyte Concentrations BECKMAN COULTER, INC. (US) 2011-04-21 US disclosed
US-7897352-B2 Adding a capture ligand for the free analyte and a stabilizing agent, an analyte and a detection system; measuring the concentration of the analyte in the sample BECKMAN COULTER, INC. (US) 2011-03-01 US disclosed
EP-2047270-A2 STABILIZING AGENTS AND CAPTURE LIGANDS FOR USE IN ASSAYS MEASURING ANALYTE CONCENTRATIONS BECKMAN Coulter, Inc. (US) 2009-04-15 EP disclosed
US-20080182341-A1 Stabilizing agents and capture ligands for use in assays measuring analyte concentrations BECKMAN COULTER, INC. 2008-07-31 US disclosed
WO-2008039266-A2 STABILIZING AGENTS AND CAPTURE LIGANDS FOR USE IN ASSAYS MEASURING ANALYTE CONCENTRATIONS BECKMAN COULTER, INC. (US) 2008-04-03 WO disclosed