Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 12/20 | 0.49 |
| ▸ | NOTUM | Q6P988 | 7/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25015342 | 0.95 | NOTUM (0.47) | HSD17B3NOTUMKDM4EHTTSMN1; SMN2 | |
| SCHEMBL14887434 | 0.86 | HSD17B3 (0.50) | HSD17B3NOTUMKDM4EHTTSMN1; SMN2 | |
| SCHEMBL22512575 | 0.84 | HSD17B3 (0.48) | HSD17B3NOTUMKDM4E | |
| SCHEMBL25963258 | 0.83 | NOTUM (0.35) | HSD17B3NOTUMKDM4EHTTSMN1; SMN2 | |
| SCHEMBL21602832 | 0.83 | HTT (0.49) | HSD17B3NOTUMKDM4EHTTSMN1; SMN2 | |
| SCHEMBL15606230 | 0.83 | HSD17B3 (0.47) | HSD17B3NOTUMKDM4EHTTSMN1; SMN2 | |
| SCHEMBL20215065 | 0.83 | HSD17B3 (0.47) | HSD17B3NOTUMKDM4EHTTSMN1; SMN2 | |
| SCHEMBL17469577 | 0.82 | HSD17B3 (0.46) | HSD17B3NOTUMKDM4EHTTSMN1; SMN2 | |
| SCHEMBL24506189 | 0.82 | DRD4 (0.33) | KDM4ESMN1; SMN2 | |
| SCHEMBL24923619 | 0.81 | KDM4E (0.32) | KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024146920-A1 | DRUG CONJUGATES FOR THE TREATMENT OF OCULAR DISORDERS | ASCENDIS PHARMA OPHTHALMOLOGY DIVISION A/S (DK) | 2024-07-11 | — | — | WO | disclosed |
| WO-2024146902-A1 | METHODS OF PRODUCING HYDROGEL MICROSPHERES | ASCENDIS PHARMA A/S (DK) | 2024-07-11 | — | — | WO | disclosed |
| WO-2023014988-A1 | CONJUGATES COMPRISING COVALENT BINDERS FOR TARGETING INTRACELLULAR PROTEINS | RAYZEBIO, INC. (US) | 2023-02-09 | — | — | WO | disclosed |
| WO-2020064844-A1 | TREATMENT OF INFECTIONS | ASCENDIS PHARMA A/S (DK) | 2020-04-02 | — | — | WO | disclosed |
| WO-2014124316-A2 | SPECIFIC SITES FOR MODIFYING ANTIBODIES TO MAKE IMMUNOCONJUGATES | IRM LLC (BM) | 2014-08-14 | — | — | WO | disclosed |