Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | HSD17B3 | P37058 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25015342 | 0.88 | NOTUM (0.47) | HTTSMN1; SMN2KDM4ENOTUMHSD17B3 | |
| SCHEMBL16204548 | 0.87 | SMN1; SMN2 (0.50) | HTTSMN1; SMN2KDM4EADORA1CES1 | |
| SCHEMBL17903051 | 0.86 | SMN1; SMN2 (0.49) | HTTSMN1; SMN2KDM4EADORA1CES1 | |
| SCHEMBL23280914 | 0.85 | KDM4E (0.48) | HTTSMN1; SMN2KDM4EADORA1CES1 | |
| SCHEMBL25963258 | 0.84 | NOTUM (0.35) | HTTSMN1; SMN2KDM4ENOTUMHSD17B3 | |
| SCHEMBL15948103 | 0.83 | HSD17B3 (0.49) | HTTSMN1; SMN2KDM4ENOTUMHSD17B3 | |
| SCHEMBL15958791 | 0.83 | KDM4E (0.50) | HTTSMN1; SMN2KDM4EADORA1CES1 | |
| SCHEMBL14315405 | 0.82 | KDM4E (0.49) | HTTSMN1; SMN2KDM4EADORA1CES1 | |
| SCHEMBL19387290 | 0.81 | KDM4E (0.48) | HTTSMN1; SMN2KDM4EADORA1CES1 | |
| SCHEMBL22472682 | 0.80 | KDM4E (0.47) | HTTSMN1; SMN2KDM4EADORA1CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019242691-A1 | PACLITAXEL-LIPID-POLYSACCHARIDE DUAL-TYPE CONJUGATE, PREPARATION METHOD THEREFOR AND USE THEREOF | 圣多利康制药责任有限公司 | 2019-12-26 | — | — | WO | disclosed |