Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAP | Q12884 | 2/20 | 0.61 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.61 |
| ▸ | POLA1 | P09884 | 1/20 | 0.61 |
| ▸ | POLG | P54098 | 1/20 | 0.61 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.61 |
| ▸ | ADCY5 | O95622 | 7/20 | 0.51 |
| ▸ | STING1 | Q86WV6 | 3/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15948882 | 1.00 | FAP (0.61) | FAPABCB11POLA1POLGSLC22A6 | |
| SCHEMBL15948658 | 0.86 | FAP (0.62) | FAPABCB11POLA1POLGSLC22A6 | |
| SCHEMBL15948858 | 0.84 | ADCY5 (0.56) | ADCY5ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL19052991 | 0.83 | FAP (0.56) | FAPABCB11POLA1POLGSLC22A6 | |
| SCHEMBL19052750 | 0.83 | FAP (0.56) | FAPABCB11POLA1POLGSLC22A6 | |
| SCHEMBL15948884 | 0.83 | ADCY5 (0.59) | ADCY5ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL10421735 | 0.80 | ADCY5 (0.60) | SLC22A6ADCY5ADORA2AADORA3ADORA2B | |
| SCHEMBL15948724 | 0.80 | ADCY5 (0.60) | SLC22A6ADCY5ADORA2AADORA3ADORA2B | |
| SCHEMBL8660803 | 0.78 | ADCY5 (0.65) | ADCY5ADORA2AADORA3ADORA2BADORA1 | |
| Adefovir Dipivoxil SCHEMBL5845498 | 0.76 | FAP (1.00) | FAPABCB11POLA1POLGSLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014124430-A1 | NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO | EMORY UNIVERSITY (US) | 2014-08-14 | — | — | WO | disclosed |