Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALB | P02768 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TK1 | P04183 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17772358 | 0.88 | TYMP (0.41) | TYMPALDH1A1LMNAALBPOLB | |
| SCHEMBL14217432 | 0.85 | CYP1A2 (0.39) | TYMPALDH1A1BLMTK1SMN1; SMN2 | |
| SCHEMBL12463863 | 0.85 | CYP1A2 (0.39) | TYMPALDH1A1BLMTK1SMN1; SMN2 | |
| SCHEMBL6998418 | 0.80 | MAPK1 (0.43) | TYMPALDH1A1LMNAALBPOLB | |
| SCHEMBL10474572 | 0.80 | TYMP (0.42) | TYMPALDH1A1LMNAALBPOLB | |
| SCHEMBL24264290 | 0.79 | TYMP (0.50) | TYMPALDH1A1LMNAALBPOLB | |
| SCHEMBL17787457 | 0.78 | TYMP (0.43) | TYMPALDH1A1LMNAALBPOLB | |
| SCHEMBL26781724 | 0.78 | TYMP (0.47) | TYMPALDH1A1LMNAALBPOLB | |
| SCHEMBL24420167 | 0.78 | TYMP (0.47) | TYMPALDH1A1LMNAALBPOLB | |
| SCHEMBL25764429 | 0.78 | TYMP (0.47) | TYMPALDH1A1LMNAALBPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014124430-A1 | NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO | EMORY UNIVERSITY (US) | 2014-08-14 | — | — | WO | disclosed |