Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.38 |
| ▸ | NT5E | P21589 | 4/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | TRAP1 | Q12931 | 1/20 | 0.33 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14568627 | 0.86 | NT5E (0.40) | HSP90AA1NT5EHDAC6HDAC1HDAC4 | |
| SCHEMBL20692015 | 0.82 | PRMT5 (0.44) | METTL3 | |
| SCHEMBL10268781 | 0.81 | TLR7 (0.48) | TLR7 | |
| SCHEMBL8620551 | 0.80 | NT5E (0.49) | NT5E | |
| SCHEMBL8620546 | 0.80 | NT5E (0.49) | NT5E | |
| SCHEMBL14544484 | 0.78 | ABL1 (0.43) | HSP90AA1HDAC6HDAC1HDAC4TRAP1 | |
| SCHEMBL1738382 | 0.78 | PDE2A (0.53) | NT5EMETTL3 | |
| SCHEMBL1738386 | 0.78 | PDE2A (0.53) | NT5EMETTL3 | |
| SCHEMBL15948682 | 0.78 | NT5E (0.42) | HSP90AA1NT5EHDAC6 | |
| SCHEMBL9127612 | 0.77 | METTL3 (0.37) | NT5EMETTL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014124430-A1 | NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO | EMORY UNIVERSITY (US) | 2014-08-14 | — | — | WO | disclosed |