Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 9/20 | 0.41 |
| ▸ | WDR77 | Q9BQA1 | 6/20 | 0.41 |
| ▸ | NT5E | P21589 | 2/20 | 0.40 |
| ▸ | BCHE | P06276 | 2/20 | 0.40 |
| ▸ | ADK | P55263 | 3/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | ABL2 | P42684 | 1/20 | 0.36 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15948738 | 0.91 | NT5E (0.38) | PRMT5WDR77NT5EBCHEADK | |
| SCHEMBL9850186 | 0.86 | BCHE (0.53) | NT5EBCHEEGFRADORA1 | |
| SCHEMBL9850184 | 0.86 | BCHE (0.53) | NT5EBCHEEGFRADORA1 | |
| SCHEMBL2670036 | 0.82 | NT5E (0.41) | NT5EBCHE | |
| SCHEMBL2670038 | 0.82 | NT5E (0.41) | NT5EBCHE | |
| SCHEMBL1738642 | 0.78 | HSP90AA1 (0.40) | NT5EBCHE | |
| SCHEMBL1738640 | 0.78 | HSP90AA1 (0.40) | NT5EBCHE | |
| SCHEMBL29365865 | 0.78 | ADK (0.50) | PRMT5WDR77BCHEADK | |
| SCHEMBL22206323 | 0.77 | NT5E (0.66) | NT5E | |
| SCHEMBL20305252 | 0.77 | NT5E (0.66) | NT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014124430-A1 | NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO | EMORY UNIVERSITY (US) | 2014-08-14 | — | — | WO | disclosed |