Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY2 | P41231 | 14/20 | 0.42 |
| ▸ | P2RY4 | P51582 | 10/20 | 0.42 |
| ▸ | POLA1 | P09884 | 1/20 | 0.42 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.41 |
| ▸ | P2RY6 | Q15077 | 9/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15948840 | 0.84 | P2RY2 (0.41) | P2RY2P2RY4POLA1ENPP1P2RY6 | |
| SCHEMBL25712429 | 0.84 | P2RY2 (0.44) | P2RY2P2RY4POLA1ENPP1P2RY6 | |
| SCHEMBL15948845 | 0.80 | POLG (0.43) | P2RY2P2RY4ENPP1P2RY6 | |
| SCHEMBL25580928 | 0.78 | P2RY2 (0.45) | P2RY2P2RY4POLA1ENPP1P2RY6 | |
| SCHEMBL22475106 | 0.78 | P2RY2 (0.43) | P2RY2P2RY4POLA1ENPP1P2RY6 | |
| SCHEMBL18474904 | 0.78 | ENPP1 (0.44) | P2RY2P2RY4POLA1ENPP1P2RY6 | |
| SCHEMBL16224817 | 0.76 | P2RY2 (0.42) | P2RY2P2RY4POLA1ENPP1P2RY6 | |
| SCHEMBL24058569 | 0.76 | P2RY2 (0.38) | P2RY2P2RY4POLA1ENPP1P2RY6 | |
| SCHEMBL18877153 | 0.75 | P2RY2 (0.42) | P2RY2P2RY4POLA1ENPP1P2RY6 | |
| SCHEMBL22475027 | 0.75 | P2RY2 (0.44) | P2RY2P2RY4POLA1ENPP1P2RY6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014124430-A1 | NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO | EMORY UNIVERSITY (US) | 2014-08-14 | — | — | WO | disclosed |