Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLG | P54098 | 4/20 | 0.43 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.36 |
| ▸ | P2RY2 | P41231 | 7/20 | 0.35 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | P2RY4 | P51582 | 4/20 | 0.33 |
| ▸ | P2RY6 | Q15077 | 3/20 | 0.33 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.33 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15281860 | 0.82 | POLG (0.41) | POLGENPP1P2RY2ENPP3FGFR1 | |
| SCHEMBL16374106 | 0.82 | POLG (0.42) | POLGENPP1P2RY2ENPP3FGFR1 | |
| SCHEMBL25586466 | 0.81 | POLG (0.41) | POLGENPP1P2RY2ENPP3FGFR1 | |
| SCHEMBL15948839 | 0.80 | P2RY2 (0.42) | ENPP1P2RY2P2RY4P2RY6 | |
| SCHEMBL13951646 | 0.78 | POLG (0.41) | POLGENPP1P2RY2ENPP3FGFR1 | |
| SCHEMBL25581105 | 0.78 | POLG (0.44) | POLGENPP1P2RY2ENPP3FGFR1 | |
| SCHEMBL20227050 | 0.78 | POLG (0.42) | POLGENPP1P2RY2ENPP3FGFR1 | |
| SCHEMBL16374058 | 0.77 | POLG (0.41) | POLGENPP1P2RY2ENPP3FGFR1 | |
| SCHEMBL15948843 | 0.77 | POLG (0.55) | POLGENPP1ENPP3POLB | |
| SCHEMBL21286470 | 0.77 | FGFR1 (0.40) | POLGP2RY2FGFR1POLBSLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014124430-A1 | NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO | EMORY UNIVERSITY (US) | 2014-08-14 | — | — | WO | disclosed |