Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.48 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.34 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.33 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | RXRB | P28702 | 1/20 | 0.32 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.32 |
| ▸ | PRKCZ | Q05513 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL365164 | 0.87 | GPBAR1 (0.37) | GPBAR1TNKS2POLB | |
| SCHEMBL15949284 | 0.87 | GPBAR1 (0.60) | GPBAR1EZH2RXRARXRBCHEK2 | |
| SCHEMBL15949291 | 0.81 | PTGS2 (0.34) | GPBAR1ADRB1ADRB3 | |
| SCHEMBL363178 | 0.81 | GPBAR1 (0.51) | GPBAR1SRD5A2RXRARXRBPPARG | |
| SCHEMBL10241335 | 0.79 | GPBAR1 (0.51) | GPBAR1SRD5A2RXRARXRBPPARG | |
| SCHEMBL10241339 | 0.79 | GPBAR1 (0.51) | GPBAR1SRD5A2RXRARXRBPPARG | |
| SCHEMBL1390130 | 0.79 | GPBAR1 (0.51) | GPBAR1SRD5A2RXRARXRBPPARG | |
| SCHEMBL369931 | 0.79 | GPBAR1 (0.51) | GPBAR1SRD5A2RXRARXRBPPARG | |
| SCHEMBL369930 | 0.79 | GPBAR1 (0.51) | GPBAR1SRD5A2RXRARXRBPPARG | |
| SCHEMBL363135 | 0.78 | GPBAR1 (0.78) | GPBAR1SRD5A2RXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593426-B1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | HOFFMANN LA ROCHE (CH) | 2014-08-20 | — | — | EP | claimed |