Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 2/20 | 0.38 |
| ▸ | CES1 | P23141 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | ALPG | P10696 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL365798 | 0.83 | GAA (0.37) | DPP4CES2CES1LMNASMN1; SMN2 | |
| SCHEMBL362884 | 0.73 | MAPK1 (0.37) | LMNASMN1; SMN2ALDH1A1HPGDNPSR1 | |
| SCHEMBL15949147 | 0.73 | SMN1; SMN2 (0.38) | LMNASMN1; SMN2ALDH1A1HPGDNPSR1 | |
| SCHEMBL28783966 | 0.73 | KMT2A (0.49) | LMNASMN1; SMN2HTTTDP1CTSK | |
| SCHEMBL15949011 | 0.73 | ACP3 (0.41) | LMNASMN1; SMN2ALDH1A1CTSKPPARG | |
| SCHEMBL362997 | 0.72 | DPP4 (0.41) | DPP4CES2CES1IDO1TDO2 | |
| SCHEMBL11031813 | 0.72 | LMNA (0.56) | LMNASMN1; SMN2ALDH1A1ALPGHPGD | |
| SCHEMBL4493580 | 0.70 | DPP4 (0.44) | DPP4CES2CES1LMNASMN1; SMN2 | |
| SCHEMBL5709450 | 0.69 | PPARG (0.42) | CES2CES1PPARG | |
| SCHEMBL20876025 | 0.67 | LMNA (0.49) | LMNASMN1; SMN2ALDH1A1ALPGHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593426-B1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | HOFFMANN LA ROCHE (CH) | 2014-08-20 | — | — | EP | disclosed |