Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 3/20 | 0.36 |
| ▸ | BRD2 | P25440 | 1/20 | 0.36 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.36 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.36 |
| ▸ | F9 | P00740 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CTSA | P10619 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15949037 | 1.00 | BRD4 (0.36) | BRD4BRD2BRD3BRDTF9 | |
| SCHEMBL15949041 | 1.00 | BRD4 (0.36) | BRD4BRD2BRD3BRDTF9 | |
| SCHEMBL1390100 | 0.92 | BRD4 (0.40) | BRD4F9HTTMEN1KMT2A | |
| SCHEMBL369846 | 0.92 | BRD4 (0.40) | BRD4F9HTTMEN1KMT2A | |
| SCHEMBL1390102 | 0.92 | BRD4 (0.40) | BRD4F9HTTMEN1KMT2A | |
| SCHEMBL370834 | 0.90 | F9 (0.38) | BRD4F9HTTKMT2AGPBAR1 | |
| SCHEMBL1389650 | 0.90 | HPGD (0.37) | BRD4BRD2BRD3BRDTCREBBP | |
| SCHEMBL1389788 | 0.90 | OPRD1 (0.37) | BRD4F9HTTMEN1KMT2A | |
| SCHEMBL1389780 | 0.90 | OPRD1 (0.37) | BRD4F9HTTMEN1KMT2A | |
| SCHEMBL1389652 | 0.90 | HPGD (0.37) | BRD4BRD2BRD3BRDTCREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593426-B1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | HOFFMANN LA ROCHE (CH) | 2014-08-20 | — | — | EP | disclosed |