SCHEMBL1594907

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL8157379	0.82	PIM1 (0.53)	PIM1PIM3PTGS1PTGS2AR
	SCHEMBL12706160	0.81	GSK3B (0.46)	CDK2AKT1SGK1PRKCZGSK3B
	SCHEMBL31729631	0.81	GSK3B (0.46)	CDK2AKT1SGK1PRKCZGSK3B
	SCHEMBL1600580	0.79	CDK2 (0.45)	CDK2AKT1SGK1PIM1AR
	SCHEMBL14260753	0.78	KDM4E (0.59)	CDK2AKT1SGK1PIM1PIM3
	SCHEMBL1594955	0.78	KDM4E (0.57)	CDK2AKT1SGK1PRKCZMEN1
	SCHEMBL14549144	0.78	CDK2 (0.44)	CDK2AKT1SGK1ARPRKCZ
	SCHEMBL1595225	0.75	CDK2 (0.41)	CDK2AKT1SGK1PIM1AR
	SCHEMBL1595231	0.75	CDK2 (0.42)	CDK2AKT1SGK1PIM1PIM3
	SCHEMBL1594532	0.74	PTGS1 (0.43)	PIM1PIM3PTGS1PTGS2PIM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.