Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 6/20 | 0.63 |
| ▸ | CTSA | P10619 | 7/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15949285 | 0.90 | GPBAR1 (0.56) | GPBAR1CTSAMAPTALDH1A1CHEK2 | |
| SCHEMBL15949337 | 0.90 | GPBAR1 (0.79) | GPBAR1CTSAMAPTALDH1A1TDP1 | |
| SCHEMBL15949282 | 0.90 | GPBAR1 (0.79) | GPBAR1CTSAMAPTALDH1A1TDP1 | |
| SCHEMBL15949249 | 0.90 | GPBAR1 (0.79) | GPBAR1CTSAMAPTALDH1A1TDP1 | |
| SCHEMBL15949232 | 0.90 | GPBAR1 (0.79) | GPBAR1CTSAMAPTALDH1A1TDP1 | |
| SCHEMBL15949051 | 0.90 | GPBAR1 (0.79) | GPBAR1CTSAMAPTALDH1A1TDP1 | |
| SCHEMBL370900 | 0.88 | GPBAR1 (0.80) | GPBAR1CTSACHEK2LMNA | |
| SCHEMBL1390281 | 0.88 | GPBAR1 (0.80) | GPBAR1CTSACHEK2LMNA | |
| SCHEMBL370898 | 0.88 | GPBAR1 (0.80) | GPBAR1CTSACHEK2LMNA | |
| SCHEMBL363226 | 0.88 | GPBAR1 (0.80) | GPBAR1CTSACHEK2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593426-B1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | HOFFMANN LA ROCHE (CH) | 2014-08-20 | — | — | EP | claimed |