Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 5/20 | 0.56 |
| ▸ | CTSA | P10619 | 10/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15949100 | 0.90 | GPBAR1 (0.63) | GPBAR1CTSAALDH1A1MAPTCHEK2 | |
| SCHEMBL15949183 | 0.90 | GPBAR1 (0.66) | GPBAR1CTSA | |
| SCHEMBL1389928 | 0.88 | GPBAR1 (0.71) | GPBAR1CTSACHEK2 | |
| SCHEMBL363133 | 0.88 | GPBAR1 (0.71) | GPBAR1CTSACHEK2 | |
| SCHEMBL1389923 | 0.88 | GPBAR1 (0.71) | GPBAR1CTSACHEK2 | |
| SCHEMBL1389926 | 0.88 | GPBAR1 (0.71) | GPBAR1CTSACHEK2 | |
| SCHEMBL15949337 | 0.84 | GPBAR1 (0.79) | GPBAR1CTSAALDH1A1MAPT | |
| SCHEMBL15949282 | 0.84 | GPBAR1 (0.79) | GPBAR1CTSAALDH1A1MAPT | |
| SCHEMBL15949249 | 0.84 | GPBAR1 (0.79) | GPBAR1CTSAALDH1A1MAPT | |
| SCHEMBL15949051 | 0.84 | GPBAR1 (0.79) | GPBAR1CTSAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593426-B1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | HOFFMANN LA ROCHE (CH) | 2014-08-20 | — | — | EP | claimed |