Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 6/20 | 0.72 |
| ▸ | CTSA | P10619 | 11/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15949076 | 1.00 | GPBAR1 (0.72) | GPBAR1CTSAFFAR1AAK1MGLL | |
| SCHEMBL15949322 | 0.94 | GPBAR1 (0.62) | GPBAR1CTSA | |
| SCHEMBL15949208 | 0.93 | GPBAR1 (0.72) | GPBAR1CTSA | |
| SCHEMBL15949119 | 0.91 | GPBAR1 (0.73) | GPBAR1CTSA | |
| SCHEMBL15949195 | 0.90 | GPBAR1 (0.58) | GPBAR1CTSAFFAR1AAK1MGLL | |
| SCHEMBL15949051 | 0.88 | GPBAR1 (0.79) | GPBAR1CTSA | |
| SCHEMBL15949249 | 0.88 | GPBAR1 (0.79) | GPBAR1CTSA | |
| SCHEMBL15949282 | 0.88 | GPBAR1 (0.79) | GPBAR1CTSA | |
| SCHEMBL15949232 | 0.88 | GPBAR1 (0.79) | GPBAR1CTSA | |
| SCHEMBL15949337 | 0.88 | GPBAR1 (0.79) | GPBAR1CTSA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593426-B1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | HOFFMANN LA ROCHE (CH) | 2014-08-20 | — | — | EP | claimed |