Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 5/20 | 0.58 |
| ▸ | CTSA | P10619 | 4/20 | 0.35 |
| ▸ | PPARD | Q03181 | 3/20 | 0.35 |
| ▸ | PLK1 | P53350 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.34 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | RXRG | P48443 | 1/20 | 0.33 |
| ▸ | WNT3A | P56704 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15949076 | 0.90 | GPBAR1 (0.72) | GPBAR1CTSAFFAR1AAK1MGLL | |
| SCHEMBL15949136 | 0.90 | GPBAR1 (0.72) | GPBAR1CTSAFFAR1AAK1MGLL | |
| SCHEMBL15949107 | 0.90 | GPBAR1 (0.63) | GPBAR1CTSAPLK1FFAR1WNT3A | |
| SCHEMBL1390122 | 0.88 | GPBAR1 (0.63) | GPBAR1PLK1FFAR1WNT3A | |
| SCHEMBL362778 | 0.88 | GPBAR1 (0.63) | GPBAR1PLK1FFAR1WNT3A | |
| SCHEMBL361985 | 0.86 | GPBAR1 (0.78) | GPBAR1CTSAPLK1RXRARXRB | |
| SCHEMBL1389833 | 0.86 | GPBAR1 (0.78) | GPBAR1CTSAPLK1RXRARXRB | |
| SCHEMBL15949322 | 0.84 | GPBAR1 (0.62) | GPBAR1CTSA | |
| SCHEMBL15949257 | 0.84 | GPBAR1 (0.53) | GPBAR1CTSAFFAR1AAK1 | |
| SCHEMBL15949058 | 0.84 | GPBAR1 (0.53) | GPBAR1CTSAFFAR1AAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593426-B1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | HOFFMANN LA ROCHE (CH) | 2014-08-20 | — | — | EP | claimed |