Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | USP2 | O75604 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CTSA | P10619 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15949155 | 1.00 | GPBAR1 (0.49) | GPBAR1MAPTUSP2HTTSMN1; SMN2 | |
| SCHEMBL15949091 | 0.89 | RORC (0.41) | GPBAR1MAPTUSP2HTTSMN1; SMN2 | |
| SCHEMBL15949129 | 0.89 | MAPT (0.45) | MAPTUSP2HTTSMN1; SMN2MEN1 | |
| SCHEMBL1389522 | 0.89 | GPBAR1 (0.63) | GPBAR1MAPTUSP2HTTSMN1; SMN2 | |
| SCHEMBL1389528 | 0.89 | GPBAR1 (0.63) | GPBAR1MAPTUSP2HTTSMN1; SMN2 | |
| SCHEMBL1389525 | 0.89 | GPBAR1 (0.63) | GPBAR1MAPTUSP2HTTSMN1; SMN2 | |
| SCHEMBL1389527 | 0.89 | GPBAR1 (0.63) | GPBAR1MAPTUSP2HTTSMN1; SMN2 | |
| SCHEMBL15949081 | 0.87 | GPBAR1 (0.52) | GPBAR1MAPTHTTALDH1A1RAB9A | |
| SCHEMBL363560 | 0.87 | GPBAR1 (0.52) | GPBAR1MAPTHTTALDH1A1RAB9A | |
| SCHEMBL363790 | 0.87 | GPBAR1 (0.52) | GPBAR1MAPTHTTALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593426-B1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | HOFFMANN LA ROCHE (CH) | 2014-08-20 | — | — | EP | claimed |