Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 6/20 | 0.66 |
| ▸ | CTSA | P10619 | 7/20 | 0.36 |
| ▸ | PORCN | Q9H237 | 1/20 | 0.35 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15949282 | 0.91 | GPBAR1 (0.79) | GPBAR1CTSAPORCNNR3C2ROCK2 | |
| SCHEMBL15949232 | 0.91 | GPBAR1 (0.79) | GPBAR1CTSAPORCNNR3C2ROCK2 | |
| SCHEMBL15949051 | 0.91 | GPBAR1 (0.79) | GPBAR1CTSAPORCNNR3C2ROCK2 | |
| SCHEMBL15949249 | 0.91 | GPBAR1 (0.79) | GPBAR1CTSAPORCNNR3C2ROCK2 | |
| SCHEMBL15949337 | 0.91 | GPBAR1 (0.79) | GPBAR1CTSAPORCNNR3C2ROCK2 | |
| SCHEMBL15949285 | 0.90 | GPBAR1 (0.56) | GPBAR1CTSA | |
| SCHEMBL1390161 | 0.89 | GPBAR1 (0.82) | GPBAR1CTSANR3C2 | |
| SCHEMBL1390162 | 0.89 | GPBAR1 (0.82) | GPBAR1CTSANR3C2 | |
| SCHEMBL1390160 | 0.89 | GPBAR1 (0.82) | GPBAR1CTSANR3C2 | |
| SCHEMBL365154 | 0.89 | GPBAR1 (0.82) | GPBAR1CTSANR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593426-B1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | HOFFMANN LA ROCHE (CH) | 2014-08-20 | — | — | EP | claimed |