Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 4/20 | 0.51 |
| ▸ | CTSA | P10619 | 12/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15949349 | 0.92 | GPBAR1 (0.49) | GPBAR1CTSAALDH1A1MAPT | |
| SCHEMBL362239 | 0.88 | GPBAR1 (0.66) | GPBAR1CTSA | |
| SCHEMBL362238 | 0.88 | GPBAR1 (0.66) | GPBAR1CTSA | |
| SCHEMBL15949240 | 0.85 | GPBAR1 (0.49) | GPBAR1CTSA | |
| SCHEMBL10241041 | 0.83 | GPBAR1 (0.54) | GPBAR1CTSA | |
| SCHEMBL362889 | 0.83 | GPBAR1 (0.54) | GPBAR1CTSA | |
| SCHEMBL1390297 | 0.83 | GPBAR1 (0.54) | GPBAR1CTSA | |
| SCHEMBL15949100 | 0.81 | GPBAR1 (0.63) | GPBAR1CTSAMEN1KMT2ATDP1 | |
| SCHEMBL1390249 | 0.80 | GPBAR1 (0.63) | GPBAR1CTSA | |
| SCHEMBL361773 | 0.80 | GPBAR1 (0.63) | GPBAR1CTSA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593426-B1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | HOFFMANN LA ROCHE (CH) | 2014-08-20 | — | — | EP | claimed |